Mouse Monoclonal Anti-GRB2 antibody (STJ99118)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-GRB2 antibody (STJ99118)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|Abundant SRC homology antibody|Adapter protein GRB2 antibody|ASH antibody|Ash protein antibody|EGFRBP GRB2 antibody|Epidermal growth factor receptor binding protein antibody|Epidermal growth factor receptor binding protein GRB2 antibody|GRB 2 antibody|GRB2 adapter protein antibody|Grb2 antibody|GRB2_HUMAN antibody|Grb3 3 antibody|Growth factor receptor bound protein 2 antibody|Growth factor receptor bound protein 3 antibody|Growth factor receptor-bound protein 2 antibody|HT027 antibody|MST084 antibody|MSTP084 antibody|NCKAP2 antibody|OTTHUMP00000166096 antibody|OTTHUMP00000166097 antibody|OTTHUMP00000166098 antibody|Protein ash antibody|SEM5 antibody|SH2/SH3 adapter GRB2 antibody|Anti-GRB2 antibody [Y237] (ab32037)
SCBT cat No: sc-503|sc-255|sc-365619|sc-8034|sc-17813|sc-137074|sc-28839|sc-13953|sc-137056|

Name

Anti-GRB2 antibody

Catalogue No.

STJ99118

Reactivity

Human, Mouse, Rat

Specificity

Anti-GRB2 antibody detects endogenous levels of GRB2 and does not cross-react with related proteins.

Immunogen

Recombinant protein of human GRB2.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Molecular weight

25kDa

Formulation

Anti-GRB2 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-GRB2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Abundant SRC homology antibody, Adapter protein GRB2 antibody, ASH antibody, Ash protein antibody, EGFRBP GRB2 antibody, Epidermal growth factor receptor binding protein antibody, Epidermal growth factor receptor binding protein GRB2 antibody, GRB 2 antibody, GRB2 adapter protein antibody, Grb2 antibody, GRB2_HUMAN antibody, Grb3 3 antibody, Growth factor receptor bound protein 2 antibody, Growth factor receptor bound protein 3 antibody, Growth factor receptor-bound protein 2 antibody, HT027 antibody, MST084 antibody, MSTP084 antibody, NCKAP2 antibody, OTTHUMP00000166096 antibody, OTTHUMP00000166097 antibody, OTTHUMP00000166098 antibody, Protein ash antibody, SEM5 antibody, SH2/SH3 adapter GRB2 antibody

Database links

UniProt/Swiss-Prot:P62993

Protein function

Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.; Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

Protein sequence and domain

Belongs to the GRB2/sem-5/DRK family. ; Contains 1 SH2 domain. ; Contains 2 SH3 domains. The SH3 domains mediate interaction with RALGPS1 and SHB.

Protein cellular localization

Nucleus . Cytoplasm . Endosome . Golgi apparatus .

Research area

All research areas>Signaling Intermediates>GRB
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Anti-GRB2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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