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Mouse Monoclonal Anti-Hexokinase 1 antibody (STJ99104)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Hexokinase 1 antibody.
Check alternative names for the antibodyExpand
|Brain form hexokinase antibody|Hexokinase 1 antibody|Hexokinase type I antibody|HK I antibody|HK1 ta antibody|HK1 tb antibody|HK1 tc antibody|HKI antibody|HXK1 antibody|Anti-pan-Hexokinase antibody [4D7] (ab58979)
SCBT cat No: sc-80978|sc-390517|sc-271865|sc-6518|sc-46695|sc-28885|
Anti-Hexokinase 1 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Anti-Hexokinase 1 antibody detects endogenous levels of Hexokinase 1 and does not cross-react with Hexokinase 2 and other proteins.
Purified recombinant human Hexokinase 1 protein fragments expressed in E.coli
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-Hexokinase 1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Hexokinase 1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Brain form hexokinase antibody, Hexokinase 1 antibody, Hexokinase type I antibody, HK I antibody, HK1 ta antibody, HK1 tb antibody, HK1 tc antibody, HKI antibody, HXK1 antibody
|Database links|| |
|Protein tissue specificity|| |
Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.
|Involvement in disease|| |
Hexokinase deficiency (HK deficiency) [MIM:235700]: Rare autosomal recessive disease with nonspherocytic hemolytic anemia as the predominant clinical feature. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Neuropathy, hereditary motor and sensory, Russe type (HMSNR) [MIM:605285]: An autosomal recessive progressive complex peripheral neuropathy characterized by onset in the first decade of distal lower limb weakness and muscle atrophy resulting in walking difficulties. Distal impairment of the upper limbs usually occurs later, as does proximal lower limb weakness. There is distal sensory impairment, with pes cavus and areflexia. Laboratory studies suggest that it is a myelinopathy resulting in reduced nerve conduction velocities in the demyelinating range as well as a length-dependent axonopathy. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the hexokinase family. ; Contains 2 hexokinase domains. The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Each domain can bind a single glucose and Gluc-6-P molecule.
|Protein cellular localization|| |
Mitochondrion outer membrane. Note=Its hydrophobic N-terminal sequence may be involved in membrane binding.
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St John’s Laboratory Ltd.
|Product type|| |
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