Mouse Monoclonal Anti-Hexokinase 1 antibody (STJ99104)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-Hexokinase 1 antibody (STJ99104)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

|Brain form hexokinase antibody|Hexokinase 1 antibody|Hexokinase type I antibody|HK I antibody|HK1 ta antibody|HK1 tb antibody|HK1 tc antibody|HKI antibody|HXK1 antibody|Anti-pan-Hexokinase antibody [4D7] (ab58979)
SCBT cat No: sc-80978|sc-390517|sc-271865|sc-6518|sc-46695|sc-28885|

Name

Anti-Hexokinase 1 antibody

Catalogue No.

STJ99104

Reactivity

Human, Mouse, Rat

Specificity

Anti-Hexokinase 1 antibody detects endogenous levels of Hexokinase 1 and does not cross-react with Hexokinase 2 and other proteins.

Immunogen

Purified recombinant human Hexokinase 1 protein fragments expressed in E.coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Molecular weight

102kDa

Formulation

Anti-Hexokinase 1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-Hexokinase 1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Brain form hexokinase antibody, Hexokinase 1 antibody, Hexokinase type I antibody, HK I antibody, HK1 ta antibody, HK1 tb antibody, HK1 tc antibody, HKI antibody, HXK1 antibody

Database links

UniProt/Swiss-Prot:P19367

Protein tissue specificity

Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.

Involvement in disease

Hexokinase deficiency (HK deficiency) [MIM:235700]: Rare autosomal recessive disease with nonspherocytic hemolytic anemia as the predominant clinical feature. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Neuropathy, hereditary motor and sensory, Russe type (HMSNR) [MIM:605285]: An autosomal recessive progressive complex peripheral neuropathy characterized by onset in the first decade of distal lower limb weakness and muscle atrophy resulting in walking difficulties. Distal impairment of the upper limbs usually occurs later, as does proximal lower limb weakness. There is distal sensory impairment, with pes cavus and areflexia. Laboratory studies suggest that it is a myelinopathy resulting in reduced nerve conduction velocities in the demyelinating range as well as a length-dependent axonopathy. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the hexokinase family. ; Contains 2 hexokinase domains. The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Each domain can bind a single glucose and Gluc-6-P molecule.

Protein cellular localization

Mitochondrion outer membrane. Note=Its hydrophobic N-terminal sequence may be involved in membrane binding.

Research area

All research areas>Kinases and Phosphatases>HXK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize Anti-Hexokinase 1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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