Mouse Monoclonal Anti-HP-1alpha antibody (STJ98945)


Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-HP-1alpha antibody (STJ98945)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody


|Antigen p25 antibody|CBX5 antibody|CBX5_HUMAN antibody|CG8409 antibody|Chromobox 5 antibody|Chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody|Chromobox homolog 5 antibody|Chromobox protein homolog 5 antibody|Epididymis luminal protein 25 antibody|HEL25 antibody|Heterochromatin protein 1 alpha antibody|Heterochromatin protein 1 antibody|Heterochromatin protein 1 homolog alpha antibody|HP1 alpha antibody|HP1 alpha homolog antibody|HP1 antibody|HP1A antibody|HP1Hs alpha antibody|Su(var)205 antibody|Anti-HP1 alpha antibody – ChIP Grade (ab77256)
SCBT cat No: sc-10217|sc-10215|sc-28735|sc-10210|sc-30742|sc-130446|sc-30743|


Anti-HP-1alpha antibody

Catalogue No.



Human, Mouse, Rat


Anti-HP-1alpha antibody detects endogenous HP-1alpha protein.


Recombinant Protein of HP-1alpha.









Molecular weight



Anti-HP-1alpha antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


1 mg/ml


Anti-HP-1alpha antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Antigen p25 antibody, CBX5 antibody, CBX5_HUMAN antibody, CG8409 antibody, Chromobox 5 antibody, Chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody, Chromobox homolog 5 antibody, Chromobox protein homolog 5 antibody, Epididymis luminal protein 25 antibody, HEL25 antibody, Heterochromatin protein 1 alpha antibody, Heterochromatin protein 1 antibody, Heterochromatin protein 1 homolog alpha antibody, HP1 alpha antibody, HP1 alpha homolog antibody, HP1 antibody, HP1A antibody, HP1Hs alpha antibody, Su(var)205 antibody

Protein function

Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. .

Protein sequence and domain

Contains 2 chromo domains.

Protein post-translational modifications

Phosphorylation of HP1 and LBR may be responsible for some of the alterations in chromatin organization and nuclear structure which occur at various times during the cell cycle (By similarity). Phosphorylated during interphase and possibly hyper-phosphorylated during mitosis. .; Ubiquitinated. .

Protein cellular localization

Nucleus . Chromosome . Chromosome, centromere . Note=Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase.

Research area

<a href="">All research areas</a>><a href="">Transcription Regulators</a>><a href="">HP1</a><br><a href=""&gt; (View all antibody categories related to Transcription Regulators)</a>


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St John’s Laboratory Ltd.

Product type

Primary antibody


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