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Mouse Monoclonal Anti-Hsp90 beta antibody (STJ99221)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
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SCBT cat No:
Anti-Hsp90 beta antibody
|Catalogue No.|| |
Human, Mouse, Rat, Monkey, Hamster
Anti-Hsp90 beta antibody detects endogenous levels of Hsp90 beta and does not cross-react with Hsp90 alpha and other proteins.
Purified recombinant human Hsp90 beta protein fragments expressed in E.coli
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-Hsp90 beta antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Hsp90 beta antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Database links|| |
|Protein function|| |
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. .
|Protein sequence and domain|| |
Belongs to the heat shock protein 90 family. The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
|Protein post-translational modifications|| |
Ubiquitinated in the presence of STUB1-UBE2D1 complex (in vitro). .; ISGylated. .; S-nitrosylated; negatively regulates the ATPase activity. .
|Protein cellular localization|| |
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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St John’s Laboratory Ltd.
|Product type|| |
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