Mouse Monoclonal Anti-Jak1 antibody (STJ99138)

$99.00$319.00

Reactivity: Human, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Mouse Monoclonal Anti-Jak1 antibody (STJ99138)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Anti-Jak1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

|JAK 1 antibody|JAK 1A antibody|JAK 1B antibody|JAK-1 antibody|JAK1 antibody|JAK1_HUMAN antibody|JAK1A antibody|JAK1B antibody|Janus kinase 1 (a protein tyrosine kinase) antibody|Janus kinase 1 antibody|JTK3 antibody|Tyrosine protein kinase JAK 1 antibody|Tyrosine protein kinase JAK1 antibody|Tyrosine-protein kinase JAK1 antibody|Phospho anti-JAK1 (Y1022 + Y1023) antibody [EPR1899(2)] (ab138005)
SCBT cat No: sc-136225|sc-1677|sc-376996|sc-7228|sc-277|sc-295|sc-390539|sc-34479|

Name

Anti-Jak1 antibody

Catalogue No.

STJ99138

Reactivity

Human, Rat

Specificity

Anti-Jak1 antibody detects endogenous levels of Jak1 and does not cross-react with related proteins.

Immunogen

Purified recombinant human Jak1 protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2a

Molecular weight

130kDa

Formulation

Anti-Jak1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-Jak1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

JAK 1 antibody, JAK 1A antibody, JAK 1B antibody, JAK-1 antibody, JAK1 antibody, JAK1_HUMAN antibody, JAK1A antibody, JAK1B antibody, Janus kinase 1 (a protein tyrosine kinase) antibody, Janus kinase 1 antibody, JTK3 antibody, Tyrosine protein kinase JAK 1 antibody, Tyrosine protein kinase JAK1 antibody, Tyrosine-protein kinase JAK1 antibody

Database links

UniProt/Swiss-Prot:P23458

Protein function

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529). .

Protein tissue specificity

Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue. .

Protein sequence and domain

Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. ; Contains 1 FERM domain. ; Contains 2 protein kinase domains. ; Contains 1 SH2 domain. Possesses two phosphotransferase domains. The second one probably contains the catalytic domain, while the presence of slight differences suggest a different role for domain 1. ; The FERM domain mediates interaction with JAKMIP1.

Protein post-translational modifications

Autophosphorylated (PubMed:7615558). Phosphorylated on tyrosine residues in response to interferon gamma signaling (PubMed:7615558). Dephosphorylation of Tyr-1034 and Tyr-1035 by PTPN2 negatively regulates cytokine-mediated signaling (PubMed:11909529). .

Protein cellular localization

Endomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated.

Research area

All research areas>Kinases and Phosphatases>JAK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize Anti-Jak1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!