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Mouse Monoclonal Anti-Keratin8/18 antibody (STJ99290)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Keratin8/18 antibody.
Check alternative names for the antibodyExpand
|CYK18 antibody|Cell proliferation-inducing gene 46 protein antibody|CK-18 antibody|CK-19 antibody|CK-8 antibody|CYK8 antibody|Cytokeratin-18 antibody|Cytokeratin-19 antibody|Cytokeratin-8 antibody|K19 antibody|K8 antibody|Keratin, type I cytoskeletal 18 antibody|Keratin, type I cytoskeletal 19 antibody|Keratin, type II cytoskeletal 8 antibody|Keratin-18 antibody|Keratin-19 antibody|Keratin-8 antibody|KRT18 antibody|KRT19 antibody|KRT8 antibody|PIG46 antibody|Type-II keratin Kb8 antibody|Anti-Keratin 8+18+19 antibody [2A4] (ab118855)
SCBT cat No: sc-130312|sc-58736|sc-73480|sc-58737|sc-374275|sc-8020|sc-374274|sc-374027|sc-134484|sc-101459|sc-53266|sc-52324|
|Catalogue No.|| |
Anti-Keratin8/18 antibody detects endogenous levels of keratin8/18.
Recombinant protein corresponding to full length Keratin8 of human.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-Keratin8/18 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Keratin8/18 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
CYK18 antibody, Cell proliferation-inducing gene 46 protein antibody, CK-18 antibody, CK-19 antibody, CK-8 antibody, CYK8 antibody, Cytokeratin-18 antibody, Cytokeratin-19 antibody, Cytokeratin-8 antibody, K19 antibody, K8 antibody, Keratin, type I cytoskeletal 18 antibody, Keratin, type I cytoskeletal 19 antibody, Keratin, type II cytoskeletal 8 antibody, Keratin-18 antibody, Keratin-19 antibody, Keratin-8 antibody, KRT18 antibody, KRT19 antibody, KRT8 antibody, PIG46 antibody, Type-II keratin Kb8 antibody
|Database links|| |
|Protein function|| |
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. .
|Protein tissue specificity|| |
Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. .
|Involvement in disease|| |
Cirrhosis (CIRRH) [MIM:215600]: A liver disease characterized by severe panlobular liver-cell swelling with Mallory body formation, prominent pericellular fibrosis, and marked deposits of copper. Clinical features include abdomen swelling, jaundice and pulmonary hypertension. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the intermediate filament family.
|Protein post-translational modifications|| |
Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization. .; O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.; O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.
|Protein cellular localization|| |
Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix .
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St John’s Laboratory Ltd.
|Product type|| |
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