Mouse Monoclonal Anti-Keratin8/18 antibody (STJ99290)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-Keratin8/18 antibody (STJ99290)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Anti-Keratin8/18 antibody.

Alternative names:

Check alternative names for the antibody

Expand

|CYK18 antibody|Cell proliferation-inducing gene 46 protein antibody|CK-18 antibody|CK-19 antibody|CK-8 antibody|CYK8 antibody|Cytokeratin-18 antibody|Cytokeratin-19 antibody|Cytokeratin-8 antibody|K19 antibody|K8 antibody|Keratin, type I cytoskeletal 18 antibody|Keratin, type I cytoskeletal 19 antibody|Keratin, type II cytoskeletal 8 antibody|Keratin-18 antibody|Keratin-19 antibody|Keratin-8 antibody|KRT18 antibody|KRT19 antibody|KRT8 antibody|PIG46 antibody|Type-II keratin Kb8 antibody|Anti-Keratin 8+18+19 antibody [2A4] (ab118855)
SCBT cat No: sc-130312|sc-58736|sc-73480|sc-58737|sc-374275|sc-8020|sc-374274|sc-374027|sc-134484|sc-101459|sc-53266|sc-52324|

Name

Anti-Keratin8/18 antibody

Catalogue No.

STJ99290

Reactivity

Human

Specificity

Anti-Keratin8/18 antibody detects endogenous levels of keratin8/18.

Immunogen

Recombinant protein corresponding to full length Keratin8 of human.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2a

Molecular weight

55/48kDa

Formulation

Anti-Keratin8/18 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-Keratin8/18 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

CYK18 antibody, Cell proliferation-inducing gene 46 protein antibody, CK-18 antibody, CK-19 antibody, CK-8 antibody, CYK8 antibody, Cytokeratin-18 antibody, Cytokeratin-19 antibody, Cytokeratin-8 antibody, K19 antibody, K8 antibody, Keratin, type I cytoskeletal 18 antibody, Keratin, type I cytoskeletal 19 antibody, Keratin, type II cytoskeletal 8 antibody, Keratin-18 antibody, Keratin-19 antibody, Keratin-8 antibody, KRT18 antibody, KRT19 antibody, KRT8 antibody, PIG46 antibody, Type-II keratin Kb8 antibody

Database links

UniProt/Swiss-Prot:P05787

Protein function

Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. .

Protein tissue specificity

Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. .

Involvement in disease

Cirrhosis (CIRRH) [MIM:215600]: A liver disease characterized by severe panlobular liver-cell swelling with Mallory body formation, prominent pericellular fibrosis, and marked deposits of copper. Clinical features include abdomen swelling, jaundice and pulmonary hypertension. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the intermediate filament family.

Protein post-translational modifications

Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization. .; O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.; O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.

Protein cellular localization

Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix .

Research area

All research areas>Structural Proteins>Cytokeratin
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus can customize Anti-Keratin8/18 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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