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Mouse Monoclonal Anti-KMT3C/SMYD2 antibody (STJ99036)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-KMT3C/SMYD2 antibody.
Check alternative names for the antibodyExpand
|Histone methyltransferase SMYD2 antibody|HSKM B antibody|HSKM-B antibody|HSKMB antibody|KMT3C antibody|Lysine N-methyltransferase 3C antibody|MGC119305 antibody|N lysine methyltransferase SMYD2 antibody|N-lysine methyltransferase SMYD2 antibody|SET and MYND domain containing 2 antibody|SET and MYND domain containing protein 2 antibody|SET and MYND domain-containing protein 2 antibody|Smyd2 antibody|SMYD2_HUMAN antibody|Zinc finger MYND domain containing 14 antibody|ZMYND14 antibody|Anti-KMT3C / SMYD2 antibody [EPR18672] (ab195365)
SCBT cat No:
|Catalogue No.|| |
Anti-KMT3C/SMYD2 antibody detects endogenous levels of KMT3C / SMYD2 and does not cross-react with related proteins.
Purified recombinant human KMT3C / SMYD2 protein fragments expressed in E.coli.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-KMT3C/SMYD2 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-KMT3C/SMYD2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Histone methyltransferase SMYD2 antibody, HSKM B antibody, HSKM-B antibody, HSKMB antibody, KMT3C antibody, Lysine N-methyltransferase 3C antibody, MGC119305 antibody, N lysine methyltransferase SMYD2 antibody, N-lysine methyltransferase SMYD2 antibody, SET and MYND domain containing 2 antibody, SET and MYND domain containing protein 2 antibody, SET and MYND domain-containing protein 2 antibody, Smyd2 antibody, SMYD2_HUMAN antibody, Zinc finger MYND domain containing 14 antibody, ZMYND14 antibody
|Database links|| |
|Protein function|| |
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. .
|Protein sequence and domain|| |
Belongs to the class V-like SAM-binding methyltransferase superfamily. ; Contains 1 MYND-type zinc finger. ; Contains 1 SET domain.
|Protein cellular localization|| |
Cytoplasm, cytosol . Nucleus .
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Transcription-Regulators/">Transcription Regulators</a>><a href="http://antibodyplus.com/product-tag/SMYD/">SMYD</a><br><a href="http://antibodyplus.com/product-tag/Transcription-Regulators/"> (View all antibody categories related to Transcription Regulators)</a>
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St John’s Laboratory Ltd.
|Product type|| |
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