Mouse Monoclonal Anti-KMT3C/SMYD2 antibody (STJ99036)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-KMT3C/SMYD2 antibody (STJ99036)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

|Histone methyltransferase SMYD2 antibody|HSKM B antibody|HSKM-B antibody|HSKMB antibody|KMT3C antibody|Lysine N-methyltransferase 3C antibody|MGC119305 antibody|N lysine methyltransferase SMYD2 antibody|N-lysine methyltransferase SMYD2 antibody|SET and MYND domain containing 2 antibody|SET and MYND domain containing protein 2 antibody|SET and MYND domain-containing protein 2 antibody|Smyd2 antibody|SMYD2_HUMAN antibody|Zinc finger MYND domain containing 14 antibody|ZMYND14 antibody|Anti-KMT3C / SMYD2 antibody [EPR18672] (ab195365)
SCBT cat No:

Name

Anti-KMT3C/SMYD2 antibody

Catalogue No.

STJ99036

Reactivity

Human, Mouse

Specificity

Anti-KMT3C/SMYD2 antibody detects endogenous levels of KMT3C / SMYD2 and does not cross-react with related proteins.

Immunogen

Purified recombinant human KMT3C / SMYD2 protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2b

Molecular weight

50kDa

Formulation

Anti-KMT3C/SMYD2 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-KMT3C/SMYD2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Histone methyltransferase SMYD2 antibody, HSKM B antibody, HSKM-B antibody, HSKMB antibody, KMT3C antibody, Lysine N-methyltransferase 3C antibody, MGC119305 antibody, N lysine methyltransferase SMYD2 antibody, N-lysine methyltransferase SMYD2 antibody, SET and MYND domain containing 2 antibody, SET and MYND domain containing protein 2 antibody, SET and MYND domain-containing protein 2 antibody, Smyd2 antibody, SMYD2_HUMAN antibody, Zinc finger MYND domain containing 14 antibody, ZMYND14 antibody

Database links

UniProt/Swiss-Prot:Q9NRG4

Protein function

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 ‘Lys-4’ (H3K4me) and dimethylates histone H3 ‘Lys-36’ (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates ‘Lys-370’ of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at ‘Lys-860’. .

Protein sequence and domain

Belongs to the class V-like SAM-binding methyltransferase superfamily. ; Contains 1 MYND-type zinc finger. ; Contains 1 SET domain.

Protein cellular localization

Cytoplasm, cytosol . Nucleus .

Research area

All research areas>Transcription Regulators>SMYD
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize Anti-KMT3C/SMYD2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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