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Mouse Monoclonal Anti-Lamin B1 antibody (STJ99312)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Lamin B1 antibody.
Check alternative names for the antibodyExpand
|ADLD antibody|CMD1A antibody|CMT2B1 antibody|Lamin A/C antibody|Lamin B1 antibody|Lamin B2 antibody|LMN2 antibody|LMNA antibody|LMNB1 antibody|LMNB2 antibody|Anti-Lamin B1 antibody – Nuclear Envelope Marker (ab16048)
SCBT cat No: sc-6216|sc-6217|sc-160482|sc-56143|sc-56144|sc-377000|sc-374015|sc-365214|sc-365962|sc-377001|sc-373918|sc-20682|sc-30264|
Anti-Lamin B1 antibody
|Catalogue No.|| |
Human, Mouse, Monkey
Anti-Lamin B1 antibody detects endogenous levels of Lamin B1 and does not cross-react with related proteins.
Recombinant human Lamin B1 protein.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-Lamin B1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Lamin B1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
ADLD antibody, CMD1A antibody, CMT2B1 antibody, Lamin A/C antibody, Lamin B1 antibody, Lamin B2 antibody, LMN2 antibody, LMNA antibody, LMNB1 antibody, LMNB2 antibody
|Database links|| |
|Protein function|| |
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
|Involvement in disease|| |
Leukodystrophy, demyelinating, autosomal dominant, adult-onset (ADLD) [MIM:169500]: A slowly progressive and fatal demyelinating leukodystrophy, presenting in the fourth or fifth decade of life. Clinically characterized by early autonomic abnormalities, pyramidal and cerebellar dysfunction, and symmetric demyelination of the CNS. It differs from multiple sclerosis and other demyelinating disorders in that neuropathology shows preservation of oligodendroglia in the presence of subtotal demyelination and lack of astrogliosis. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the intermediate filament family. ; Contains 1 LTD domain.
|Protein post-translational modifications|| |
B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
|Protein cellular localization|| |
Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Tumor-SuppressorApoptosis/">Tumor Suppressor/Apoptosis</a>><a href="http://antibodyplus.com/product-tag/Lamin/">Lamin</a><br><a href="http://antibodyplus.com/product-tag/Tumor-SuppressorApoptosis/"> (View all antibody categories related to Tumor Suppressor/Apoptosis)</a>
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St John’s Laboratory Ltd.
|Product type|| |
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