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Mouse Monoclonal Anti-Lamin B2 antibody (STJ99315)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Lamin B2 antibody.
Check alternative names for the antibodyExpand
|LAMB 2 antibody|LAMB2 antibody|Lamin-B2 antibody|LMN 2 antibody|LMN B2 antibody|LMN2 antibody|LMNB 2 antibody|LMNB2 antibody|LMNB2_HUMAN antibody|MGC2721 antibody|RGD1563803 antibody|Anti-Lamin B2 antibody [LN43] (ab8983)
SCBT cat No: sc-71484|sc-377379|sc-56146|sc-133722|sc-56147|
Anti-Lamin B2 antibody
|Catalogue No.|| |
Anti-Lamin B2 antibody detects endogenous levels of Lamin B2 and does not cross-react with related proteins.
Recombinant human Lamin B2 protein.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-Lamin B2 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Lamin B2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
LAMB 2 antibody, LAMB2 antibody, Lamin-B2 antibody, LMN 2 antibody, LMN B2 antibody, LMN2 antibody, LMNB 2 antibody, LMNB2 antibody, LMNB2_HUMAN antibody, MGC2721 antibody, RGD1563803 antibody
|Database links|| |
|Protein function|| |
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
|Involvement in disease|| |
Partial acquired lipodystrophy (APLD) [MIM:608709]: A rare childhood disease characterized by loss of subcutaneous fat from the face and trunk. Fat deposition on the pelvic girdle and lower limbs is normal or excessive. Most frequently, onset between 5 and 15 years of age. Most affected subjects are females and some show no other abnormality, but many develop glomerulonephritis, diabetes mellitus, hyperlipidemia, and complement deficiency. Mental retardation in some cases. APLD is a sporadic disorder of unknown etiology. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Epilepsy, progressive myoclonic 9 (EPM9) [MIM:616540]: An autosomal recessive form of progressive myoclonic epilepsy, a rare disease initially responsive to antiepileptic drugs which over time becomes refractory and can be associated with cognitive decline. EPM9 features include myoclonus, tonic-clonic seizures, ataxia, and psychomotor development. . Note=The disease may be caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the intermediate filament family. ; Contains 1 LTD domain.
|Protein post-translational modifications|| |
B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
|Protein cellular localization|| |
Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Tumor-SuppressorApoptosis/">Tumor Suppressor/Apoptosis</a>><a href="http://antibodyplus.com/product-tag/Lamin/">Lamin</a><br><a href="http://antibodyplus.com/product-tag/Tumor-SuppressorApoptosis/"> (View all antibody categories related to Tumor Suppressor/Apoptosis)</a>
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St John’s Laboratory Ltd.
|Product type|| |
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