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Mouse Monoclonal Anti-OLIG2 antibody (STJ99201)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-OLIG2 antibody.
Check alternative names for the antibodyExpand
|Basic domain helix loop helix protein class B 1 antibody|Basic helix loop helix protein class B 1 antibody|BHLHB antibody|bHLHB1 antibody|bHLHe19 antibody|Class B basic helix loop helix protein 1 antibody|Class B basic helix-loop-helix protein 1 antibody|class E basic helix loop helix protein 19 antibody|Class E basic helix-loop-helix protein 19 antibody|Human protein kinase C binding protein RACK17 antibody|Olig2 antibody|OLIG2_HUMAN antibody|Oligo2 antibody|Oligodendrocyte lineage transcription factor 2 antibody|Oligodendrocyte specific bHLH transcription factor 2 antibody|Oligodendrocyte transcription factor 2 antibody|OTTHUMP00000067569 antibody|OTTHUMP00000067570 antibody|PRKCBP2 antibody|Protein kinase C binding protein 2 antibody|Protein kinase C binding protein RACK17 antibody|Protein kinase C-binding protein 2 antibody|Protein kinase C-binding protein RACK17 antibody|RACK17 antibody|Anti-Olig2 antibody [EPR2673] (ab109186)
SCBT cat No: sc-293163|sc-19969|sc-48817|sc-19967|sc-133869|
|Catalogue No.|| |
Purified recombinant human OLIG2 beta protein fragments expressed in E.coli.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-OLIG2 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-OLIG2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Basic domain helix loop helix protein class B 1 antibody, Basic helix loop helix protein class B 1 antibody, BHLHB antibody, bHLHB1 antibody, bHLHe19 antibody, Class B basic helix loop helix protein 1 antibody, Class B basic helix-loop-helix protein 1 antibody, class E basic helix loop helix protein 19 antibody, Class E basic helix-loop-helix protein 19 antibody, Human protein kinase C binding protein RACK17 antibody, Olig2 antibody, OLIG2_HUMAN antibody, Oligo2 antibody, Oligodendrocyte lineage transcription factor 2 antibody, Oligodendrocyte specific bHLH transcription factor 2 antibody, Oligodendrocyte transcription factor 2 antibody, OTTHUMP00000067569 antibody, OTTHUMP00000067570 antibody, PRKCBP2 antibody, Protein kinase C binding protein 2 antibody, Protein kinase C binding protein RACK17 antibody, Protein kinase C-binding protein 2 antibody, Protein kinase C-binding protein RACK17 antibody, RACK17 antibody
|Database links|| |
|Protein function|| |
Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (By similarity). .
|Protein tissue specificity|| |
Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. .
|Involvement in disease|| |
Note=A chromosomal aberration involving OLIG2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(14;21)(q11.2;q22) with TCRA. .
|Protein sequence and domain|| |
Contains 1 bHLH (basic helix-loop-helix) domain. The bHLH is essential for interaction with NKX2-2.
|Protein cellular localization|| |
Nucleus . Cytoplasm . Note=The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2. .
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St John’s Laboratory Ltd.
|Product type|| |
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