Mouse Monoclonal Anti-OLIG2 antibody (STJ99201)

$99.00$319.00

Reactivity: Transfected
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-OLIG2 antibody (STJ99201)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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|Basic domain helix loop helix protein class B 1 antibody|Basic helix loop helix protein class B 1 antibody|BHLHB antibody|bHLHB1 antibody|bHLHe19 antibody|Class B basic helix loop helix protein 1 antibody|Class B basic helix-loop-helix protein 1 antibody|class E basic helix loop helix protein 19 antibody|Class E basic helix-loop-helix protein 19 antibody|Human protein kinase C binding protein RACK17 antibody|Olig2 antibody|OLIG2_HUMAN antibody|Oligo2 antibody|Oligodendrocyte lineage transcription factor 2 antibody|Oligodendrocyte specific bHLH transcription factor 2 antibody|Oligodendrocyte transcription factor 2 antibody|OTTHUMP00000067569 antibody|OTTHUMP00000067570 antibody|PRKCBP2 antibody|Protein kinase C binding protein 2 antibody|Protein kinase C binding protein RACK17 antibody|Protein kinase C-binding protein 2 antibody|Protein kinase C-binding protein RACK17 antibody|RACK17 antibody|Anti-Olig2 antibody [EPR2673] (ab109186)
SCBT cat No: sc-293163|sc-19969|sc-48817|sc-19967|sc-133869|

Name

Anti-OLIG2 antibody

Catalogue No.

STJ99201

Reactivity

Transfected

Immunogen

Purified recombinant human OLIG2 beta protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Molecular weight

32kDa

Formulation

Anti-OLIG2 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-OLIG2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Basic domain helix loop helix protein class B 1 antibody, Basic helix loop helix protein class B 1 antibody, BHLHB antibody, bHLHB1 antibody, bHLHe19 antibody, Class B basic helix loop helix protein 1 antibody, Class B basic helix-loop-helix protein 1 antibody, class E basic helix loop helix protein 19 antibody, Class E basic helix-loop-helix protein 19 antibody, Human protein kinase C binding protein RACK17 antibody, Olig2 antibody, OLIG2_HUMAN antibody, Oligo2 antibody, Oligodendrocyte lineage transcription factor 2 antibody, Oligodendrocyte specific bHLH transcription factor 2 antibody, Oligodendrocyte transcription factor 2 antibody, OTTHUMP00000067569 antibody, OTTHUMP00000067570 antibody, PRKCBP2 antibody, Protein kinase C binding protein 2 antibody, Protein kinase C binding protein RACK17 antibody, Protein kinase C-binding protein 2 antibody, Protein kinase C-binding protein RACK17 antibody, RACK17 antibody

Database links

UniProt/Swiss-Prot:Q13516

Protein function

Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (By similarity). .

Protein tissue specificity

Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. .

Involvement in disease

Note=A chromosomal aberration involving OLIG2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(14;21)(q11.2;q22) with TCRA. .

Protein sequence and domain

Contains 1 bHLH (basic helix-loop-helix) domain. The bHLH is essential for interaction with NKX2-2.

Protein cellular localization

Nucleus . Cytoplasm . Note=The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2. .

Note

AntibodyPlus can customize Anti-OLIG2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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