Mouse Monoclonal Anti-PEG10 antibody (STJ99176)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-PEG10 antibody (STJ99176)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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|AA407948 antibody|Edr antibody|Embryonal carcinoma differentiation regulated antibody|Embryonal carcinoma differentiation-regulated protein antibody|HB 1 antibody|HB1 antibody|KIAA1051 antibody|Mammalian retrotransposon-derived protein 2 antibody|Mar2 antibody|Mart2 antibody|MEF3 like 1 antibody|MEF3-like protein 1 antibody|MEF3L antibody|MEF3L1 antibody|MyEF 3 antibody|Myelin expression factor 3-like protein 1 antibody|Paternally expressed 10 antibody|Paternally expressed gene 10 ORF1 antibody|Paternally expressed gene 10 protein antibody|Peg10 antibody|PEG10 protein antibody|PEG10_HUMAN antibody|Putative uncharacterized protein PEG10 antibody|Retrotransposon gag domain containing 3 antibody|Retrotransposon gag domain-containing protein 3 antibody|Retrotransposon-derived gag-like polyprotein antibody|Retrotransposon-derived protein PEG10 antibody|RGAG3 antibody|Ty3/Gypsy-like protein antibody|Anti-PEG10 antibody [EPR20051] (ab215035)
SCBT cat No: sc-365675|sc-68899|

Name

Anti-PEG10 antibody

Catalogue No.

STJ99176

Reactivity

Human

Specificity

Anti-PEG10 antibody detects endogenous levels of PEG10 and does not cross-react with related proteins.

Immunogen

Purified recombinant human PEG10 protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Molecular weight

55kDa

Formulation

Anti-PEG10 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-PEG10 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

AA407948 antibody, Edr antibody, Embryonal carcinoma differentiation regulated antibody, Embryonal carcinoma differentiation-regulated protein antibody, HB 1 antibody, HB1 antibody, KIAA1051 antibody, Mammalian retrotransposon-derived protein 2 antibody, Mar2 antibody, Mart2 antibody, MEF3 like 1 antibody, MEF3-like protein 1 antibody, MEF3L antibody, MEF3L1 antibody, MyEF 3 antibody, Myelin expression factor 3-like protein 1 antibody, Paternally expressed 10 antibody, Paternally expressed gene 10 ORF1 antibody, Paternally expressed gene 10 protein antibody, Peg10 antibody, PEG10 protein antibody, PEG10_HUMAN antibody, Putative uncharacterized protein PEG10 antibody, Retrotransposon gag domain containing 3 antibody, Retrotransposon gag domain-containing protein 3 antibody, Retrotransposon-derived gag-like polyprotein antibody, Retrotransposon-derived protein PEG10 antibody, RGAG3 antibody, Ty3/Gypsy-like protein antibody

Database links

UniProt/Swiss-Prot:Q86TG7

Protein function

Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5′-GCCTGTCTTT-3′ DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity). .

Protein tissue specificity

Expressed in the cytotrophoblast layer but not in the overlying syncytiotrophoblast of the placenta. Expressed in prostate and breast carcinomas but not in normal breast and prostate epithelial cells. Expressed in the Hep-G2 cell line (at protein level). Expressed in brain, liver, spleen, kidney, thymus, lung, ovary, testis, reactive lymph node, skeletal muscle, adipose tissue and placenta. Expressed in pancreatic and hepatocellular carcinomas (HCC). .

Protein sequence and domain

Contains 1 CCHC-type zinc finger.

Protein post-translational modifications

Isoform 1 undergoes proteolytic cleavage. .

Protein cellular localization

Nucleus. Cytoplasm. Note=Detected predominantly in the cytoplasm of breast and prostate carcinomas, in hepatocellular carcinoma (HCC) and B-cell chronic lymphocytic leukemia (B-CLL) cells and in the Hep-G2 cell line. Colocalized with ALK1.

Research area

All research areas>Signaling Intermediates>Peg
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Anti-PEG10 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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