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Mouse Monoclonal Anti-PP2A alpha and beta antibody (STJ99088)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-PP2A alpha and beta antibody.
Check alternative names for the antibodyExpand
|PP2A beta antibody|PP2A-beta antibody|PP2AB_HUMAN antibody|PP2Abeta antibody|PP2CB antibody|Ppp2cb antibody|Protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform antibody|Protein phosphatase 2 catalytic subunit beta isozyme antibody|Protein phosphatase 2, catalytic subunit, beta isoform antibody|Protein phosphatase 2A catalytic subunit beta isoform antibody|Protein phosphatase type 2A catalytic subunit antibody|Serine/threonine protein phosphatase 2A catalytic subunit beta antibody|Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform antibody|Anti-PPP2CB antibody [EPR11786(B)] (ab168371)
SCBT cat No: sc-80990|
Anti-PP2A alpha and beta antibody
|Catalogue No.|| |
Human, Mouse, Rat
Anti-PP2A alpha and beta antibody detects endogenous levels of PP2A alpha and PP2A beta.
Purified recombinant human full length PP2A beta protein expressed in E.coli
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-PP2A alpha and beta antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-PP2A alpha and beta antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
PP2A beta antibody, PP2A-beta antibody, PP2AB_HUMAN antibody, PP2Abeta antibody, PP2CB antibody, Ppp2cb antibody, Protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform antibody, Protein phosphatase 2 catalytic subunit beta isozyme antibody, Protein phosphatase 2, catalytic subunit, beta isoform antibody, Protein phosphatase 2A catalytic subunit beta isoform antibody, Protein phosphatase type 2A catalytic subunit antibody, Serine/threonine protein phosphatase 2A catalytic subunit beta antibody, Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform antibody
|Database links|| |
|Protein function|| |
PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. .
|Protein sequence and domain|| |
Belongs to the PPP phosphatase family. PP-1 subfamily.
|Protein post-translational modifications|| |
Reversibly methyl esterified on Leu-309 by leucine carboxyl methyltransferase 1 (LCMT1) and protein phosphatase methylesterase 1 (PPME1). Carboxyl methylation influences the affinity of the catalytic subunit for the different regulatory subunits, thereby modulating the PP2A holoenzyme's substrate specificity, enzyme activity and cellular localization. .; Phosphorylation of either threonine (by autophosphorylation-activated protein kinase) or tyrosine results in inactivation of the phosphatase. Auto-dephosphorylation has been suggested as a mechanism for reactivation.; May be monoubiquitinated by NOSIP. .
|Protein cellular localization|| |
Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Kinases-and-Phosphatases/">Kinases and Phosphatases</a>><a href="http://antibodyplus.com/product-tag/PP2/">PP2</a><br><a href="http://antibodyplus.com/product-tag/Kinases-and-Phosphatases/"> (View all antibody categories related to Kinases and Phosphatases)</a>
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St John’s Laboratory Ltd.
|Product type|| |
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