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Mouse Monoclonal Anti-RanBP9 antibody (STJ99126)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-RanBP9 antibody.
Check alternative names for the antibodyExpand
|B cell antigen receptor Ig beta associated protein 1 antibody|BPM 90 antibody|BPM L antibody|BPM-L antibody|BPM90 antibody|BPML antibody|IBAP 1 antibody|Imp 9 antibody|Importin 9 antibody|Novel centrosomal protein RanBPM antibody|RAN binding protein 9 antibody|Ran binding protein centrosomal antibody|Ran Binding Protein in the Microtubule organizing center antibody|Ran binding protein M antibody|Ran BP9 antibody|Ran-binding protein 9 antibody|Ran-binding protein M antibody|RANB9_HUMAN antibody|RanBP 7 antibody|RANBP 9 antibody|RanBP7 antibody|RanBP9 antibody|RanBPM antibody|Anti-RanBP9 antibody (ab5295)
SCBT cat No: sc-271726|sc-271727|sc-67050|sc-46253|
|Catalogue No.|| |
Anti-RanBP9 antibody detects endogenous levels of RanBP9 and does not cross-react with related proteins.
Purified recombinant human RanBP9 protein fragments expressed in E.coli.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-RanBP9 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-RanBP9 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
B cell antigen receptor Ig beta associated protein 1 antibody, BPM 90 antibody, BPM L antibody, BPM-L antibody, BPM90 antibody, BPML antibody, IBAP 1 antibody, Imp 9 antibody, Importin 9 antibody, Novel centrosomal protein RanBPM antibody, RAN binding protein 9 antibody, Ran binding protein centrosomal antibody, Ran Binding Protein in the Microtubule organizing center antibody, Ran binding protein M antibody, Ran BP9 antibody, Ran-binding protein 9 antibody, Ran-binding protein M antibody, RANB9_HUMAN antibody, RanBP 7 antibody, RANBP 9 antibody, RanBP7 antibody, RanBP9 antibody, RanBPM antibody
|Database links|| |
|Protein function|| |
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA (By similarity). .
|Protein tissue specificity|| |
Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells. .
|Protein sequence and domain|| |
Belongs to the RANBP9/10 family. ; Contains 1 B30.2/SPRY domain. ; Contains 1 CTLH domain. ; Contains 1 LisH domain. The SPRY domain mediates the interaction with MET, AR, and CDC2L1.
|Protein post-translational modifications|| |
Phosphorylated in response to stress. Can be phosphorylated by the cleaved p110 form of CDC2L1 (p110C). .; Ubiquitinated. Polyubiquitination targets the protein for rapid degradation via the ubiquitin system. Can be deubiquitinated by USP11. .
|Protein cellular localization|| |
Cytoplasm . Nucleus . Cell membrane; Peripheral membrane protein . Note=The unphosphorylated form is predominantly cytoplasmic. A phosphorylated form is associated with the plasma membrane. .
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St John’s Laboratory Ltd.
|Product type|| |
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