Mouse Monoclonal Anti-SAFB1 antibody (STJ99122)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-SAFB1 antibody (STJ99122)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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|DKFZp779C1727 antibody|glutathione S transferase fusion protein antibody|HAP antibody|HET antibody|HSP27 ERE TATA binding protein antibody|HSP27 ERE-TATA-binding protein antibody|HSP27 estrogen response element-TATA box-binding protein antibody|SAF B antibody|SAF-B antibody|SAF-B1 antibody|SAFB 1 antibody|SAFB antibody|SAFB1 antibody|SAFB1_HUMAN antibody|Scaffold attachment factor B1 antibody|Anti-SAFB antibody [EPR13588] – C-terminal (ab187650)
SCBT cat No: sc-393455|sc-514963|sc-393689|

Name

Anti-SAFB1 antibody

Catalogue No.

STJ99122

Reactivity

Human

Specificity

Anti-SAFB1 antibody detects endogenous levels of SAFB1 and does not cross-react with related prote.

Immunogen

Purified recombinant human SAFB1 protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Molecular weight

130kDa

Formulation

Anti-SAFB1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-SAFB1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

DKFZp779C1727 antibody, glutathione S transferase fusion protein antibody, HAP antibody, HET antibody, HSP27 ERE TATA binding protein antibody, HSP27 ERE-TATA-binding protein antibody, HSP27 estrogen response element-TATA box-binding protein antibody, SAF B antibody, SAF-B antibody, SAF-B1 antibody, SAFB 1 antibody, SAFB antibody, SAFB1 antibody, SAFB1_HUMAN antibody, Scaffold attachment factor B1 antibody

Database links

UniProt/Swiss-Prot:Q15424

Protein function

Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a ‘transcriptosomal’ complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity). Can inhibit cell proliferation. .

Protein tissue specificity

Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.

Protein sequence and domain

Contains 1 RRM (RNA recognition motif) domain. ; Contains 1 SAP domain.

Protein post-translational modifications

Sumoylated by PIAS1 with SUMO1 and SUMO2/3, desumoylated by SENP1. Sumoylation is required for transcriptional repressor activity. .

Protein cellular localization

Nucleus .

Research area

All research areas>Transcription Regulators>SAF-B
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize Anti-SAFB1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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