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Mouse Monoclonal Anti-SAFB1 antibody (STJ99122)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-SAFB1 antibody.
Check alternative names for the antibodyExpand
|DKFZp779C1727 antibody|glutathione S transferase fusion protein antibody|HAP antibody|HET antibody|HSP27 ERE TATA binding protein antibody|HSP27 ERE-TATA-binding protein antibody|HSP27 estrogen response element-TATA box-binding protein antibody|SAF B antibody|SAF-B antibody|SAF-B1 antibody|SAFB 1 antibody|SAFB antibody|SAFB1 antibody|SAFB1_HUMAN antibody|Scaffold attachment factor B1 antibody|Anti-SAFB antibody [EPR13588] – C-terminal (ab187650)
SCBT cat No: sc-393455|sc-514963|sc-393689|
|Catalogue No.|| |
Anti-SAFB1 antibody detects endogenous levels of SAFB1 and does not cross-react with related prote.
Purified recombinant human SAFB1 protein fragments expressed in E.coli.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-SAFB1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-SAFB1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
DKFZp779C1727 antibody, glutathione S transferase fusion protein antibody, HAP antibody, HET antibody, HSP27 ERE TATA binding protein antibody, HSP27 ERE-TATA-binding protein antibody, HSP27 estrogen response element-TATA box-binding protein antibody, SAF B antibody, SAF-B antibody, SAF-B1 antibody, SAFB 1 antibody, SAFB antibody, SAFB1 antibody, SAFB1_HUMAN antibody, Scaffold attachment factor B1 antibody
|Database links|| |
|Protein function|| |
Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity). Can inhibit cell proliferation. .
|Protein tissue specificity|| |
Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
|Protein sequence and domain|| |
Contains 1 RRM (RNA recognition motif) domain. ; Contains 1 SAP domain.
|Protein post-translational modifications|| |
Sumoylated by PIAS1 with SUMO1 and SUMO2/3, desumoylated by SENP1. Sumoylation is required for transcriptional repressor activity. .
|Protein cellular localization|| |
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Transcription-Regulators/">Transcription Regulators</a>><a href="http://antibodyplus.com/product-tag/SAF-B/">SAF-B</a><br><a href="http://antibodyplus.com/product-tag/Transcription-Regulators/"> (View all antibody categories related to Transcription Regulators)</a>
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St John’s Laboratory Ltd.
|Product type|| |
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