Mouse Monoclonal Anti-SWAP70 antibody (STJ99160)

$99.00$319.00

Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Mouse Monoclonal Anti-SWAP70 antibody (STJ99160)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Anti-SWAP70 antibody.

Alternative names:

Check alternative names for the antibody

Expand

|KIAA0640 antibody|70kDa antibody|AV235546 antibody|FLJ39540 antibody|HSPC321 antibody|SWA 70 protein antibody|SWAP 70 antibody|SWAP switching B-cell complex 70kDa subunit antibody|SWAP-70 antibody|SWAP70 antibody|Switch associated protein 70 antibody|Switch-associated protein 70 antibody|SWP70_HUMAN antibody|Anti-SWAP70 antibody (ab150325)
SCBT cat No:

Name

Anti-SWAP70 antibody

Catalogue No.

STJ99160

Reactivity

Human, Mouse, Rat, Monkey

Specificity

Anti-SWAP70 antibody detects endogenous levels of SWAP70 and does not cross-react with related proteins.

Immunogen

Purified recombinant human SWAP70 protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2b

Molecular weight

70kDa

Formulation

Anti-SWAP70 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-SWAP70 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

KIAA0640 antibody, 70kDa antibody, AV235546 antibody, FLJ39540 antibody, HSPC321 antibody, SWA 70 protein antibody, SWAP 70 antibody, SWAP switching B-cell complex 70kDa subunit antibody, SWAP-70 antibody, SWAP70 antibody, Switch associated protein 70 antibody, Switch-associated protein 70 antibody, SWP70_HUMAN antibody

Database links

UniProt/Swiss-Prot:Q9UH65

Protein function

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). .

Protein tissue specificity

Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus-associated tissue (PubMed:10681448). Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages (PubMed:12925760). .

Protein sequence and domain

Contains 1 PH domain. The PH domain is essential for phosphatidylinositol 3,4,5-trisphosphate binding.

Protein post-translational modifications

Tyrosine-phosphorylated. .

Protein cellular localization

Cytoplasm . Cell membrane. Nucleus . Cell projection, lamellipodium . Cytoplasm, cytoskeleton . Note=In resting B-cells it is localized mainly in the cytoplasm and upon cell activation it is recruited to the plasma membrane and then translocates to the nucleus (PubMed:10681448). In activated, class-switching B-cells it is associated with membrane IgG but not IgM (PubMed:10681448). Localized to loose actin filament arrays located behind actively extending lamellipodia (PubMed:12925760). .

Research area

All research areas>Lymphocyte Signaling>SWAP-70
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize Anti-SWAP70 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!