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Mouse Monoclonal Anti-Toll-like Receptor 7 antibody (STJ99313)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Toll-like Receptor 7 antibody.
Check alternative names for the antibodyExpand
|PRO285 antibody|TLR 7 antibody|Tlr7 antibody|TLR7_HUMAN antibody|Toll like receptor 7 antibody|Toll-like receptor 7 antibody|UNQ248 antibody|Anti-TLR7 antibody (ab45371)
SCBT cat No:
Anti-Toll-like Receptor 7 antibody
|Catalogue No.|| |
Anti-Toll-like Receptor 7 antibody detects endogenous levels of Toll-like Receptor and does not cross-react with related proteins.
Purified recombinant human Toll-like Receptor protein fragments expressed in E.coli.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
Anti-Toll-like Receptor 7 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Toll-like Receptor 7 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
PRO285 antibody, TLR 7 antibody, Tlr7 antibody, TLR7_HUMAN antibody, Toll like receptor 7 antibody, Toll-like receptor 7 antibody, UNQ248 antibody
|Database links|| |
|Protein function|| |
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). .
|Protein tissue specificity|| |
Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
|Protein sequence and domain|| |
Belongs to the Toll-like receptor family. ; Contains 27 LRR (leucine-rich) repeats. ; Contains 1 TIR domain.
|Protein cellular localization|| |
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endosome . Lysosome . Cytoplasmic vesicle, phagosome . Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. .
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St John’s Laboratory Ltd.
|Product type|| |
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