Mouse Monoclonal Anti-VE-Cadherin antibody (STJ98913)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-VE-Cadherin antibody (STJ98913)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|7B 4 antibody|7B4 antibody|7B4 antigen antibody|CADH5_HUMAN antibody|Cadherin 5 antibody|Cadherin 5 type 2 antibody|Cadherin 5, type 2 (vascular endothelium) antibody|Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody|cadherin, vascular endothelial antibody|cadherin, vascular endothelial, 1 antibody|Cadherin-5 antibody|Cadherin5 antibody|CD 144 antibody|CD144 antibody|CD144 antigen antibody|CDH 5 antibody|CDH5 antibody|CDH5 protein antibody|Endothelial specific cadherin antibody|FLJ17376 antibody|OTTHUMP00000174777 antibody|Vascular endothelial cadherin antibody|Vascular epithelium cadherin antibody|VE Cad antibody|VE-cadherin antibody|VEC antibody|Anti-VE Cadherin antibody – Intercellular Junction Marker (ab33168)
SCBT cat No:

Name

Anti-VE-Cadherin antibody

Catalogue No.

STJ98913

Reactivity

Human, Mouse, Rat

Specificity

Anti-VE-Cadherin antibody detects endogenous VE-Cadherin protein.

Immunogen

Synthetic Peptide of VE-Cadherin.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Molecular weight

80-115kDa

Formulation

Anti-VE-Cadherin antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-VE-Cadherin antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

7B 4 antibody, 7B4 antibody, 7B4 antigen antibody, CADH5_HUMAN antibody, Cadherin 5 antibody, Cadherin 5 type 2 antibody, Cadherin 5, type 2 (vascular endothelium) antibody, Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody, cadherin, vascular endothelial antibody, cadherin, vascular endothelial, 1 antibody, Cadherin-5 antibody, Cadherin5 antibody, CD 144 antibody, CD144 antibody, CD144 antigen antibody, CDH 5 antibody, CDH5 antibody, CDH5 protein antibody, Endothelial specific cadherin antibody, FLJ17376 antibody, OTTHUMP00000174777 antibody, Vascular endothelial cadherin antibody, Vascular epithelium cadherin antibody, VE Cad antibody, VE-cadherin antibody, VEC antibody

Database links

UniProt/Swiss-Prot:P33151

Protein function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction. .

Protein tissue specificity

Endothelial tissues and brain.

Protein sequence and domain

Contains 5 cadherin domains. Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.

Protein post-translational modifications

Phosphorylated on tyrosine residues by KDR/VEGFR-2. Dephosphorylated by PTPRB (By similarity). .; O-glycosylated. .

Protein cellular localization

Cell junction . Cell membrane ; Single-pass type I membrane protein . Note=Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions.

Note

AntibodyPlus can customize Anti-VE-Cadherin antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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