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Mouse Monoclonal Anti-VE-Cadherin antibody (STJ98913)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-VE-Cadherin antibody.
Check alternative names for the antibodyExpand
|7B 4 antibody|7B4 antibody|7B4 antigen antibody|CADH5_HUMAN antibody|Cadherin 5 antibody|Cadherin 5 type 2 antibody|Cadherin 5, type 2 (vascular endothelium) antibody|Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody|cadherin, vascular endothelial antibody|cadherin, vascular endothelial, 1 antibody|Cadherin-5 antibody|Cadherin5 antibody|CD 144 antibody|CD144 antibody|CD144 antigen antibody|CDH 5 antibody|CDH5 antibody|CDH5 protein antibody|Endothelial specific cadherin antibody|FLJ17376 antibody|OTTHUMP00000174777 antibody|Vascular endothelial cadherin antibody|Vascular epithelium cadherin antibody|VE Cad antibody|VE-cadherin antibody|VEC antibody|Anti-VE Cadherin antibody – Intercellular Junction Marker (ab33168)
SCBT cat No:
|Catalogue No.|| |
Human, Mouse, Rat
Anti-VE-Cadherin antibody detects endogenous VE-Cadherin protein.
Synthetic Peptide of VE-Cadherin.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-VE-Cadherin antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-VE-Cadherin antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
7B 4 antibody, 7B4 antibody, 7B4 antigen antibody, CADH5_HUMAN antibody, Cadherin 5 antibody, Cadherin 5 type 2 antibody, Cadherin 5, type 2 (vascular endothelium) antibody, Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody, cadherin, vascular endothelial antibody, cadherin, vascular endothelial, 1 antibody, Cadherin-5 antibody, Cadherin5 antibody, CD 144 antibody, CD144 antibody, CD144 antigen antibody, CDH 5 antibody, CDH5 antibody, CDH5 protein antibody, Endothelial specific cadherin antibody, FLJ17376 antibody, OTTHUMP00000174777 antibody, Vascular endothelial cadherin antibody, Vascular epithelium cadherin antibody, VE Cad antibody, VE-cadherin antibody, VEC antibody
|Database links|| |
|Protein function|| |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction. .
|Protein tissue specificity|| |
Endothelial tissues and brain.
|Protein sequence and domain|| |
Contains 5 cadherin domains. Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
|Protein post-translational modifications|| |
Phosphorylated on tyrosine residues by KDR/VEGFR-2. Dephosphorylated by PTPRB (By similarity). .; O-glycosylated. .
|Protein cellular localization|| |
Cell junction . Cell membrane ; Single-pass type I membrane protein . Note=Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions.
AntibodyPlus can customize Anti-VE-Cadherin antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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