Mouse Monoclonal Anti-WDR77 antibody (STJ99206)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-WDR77 antibody (STJ99206)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|2610312E17Rik antibody|Androgen receptor cofactor p44 antibody|C79984 antibody|HKMT1069 antibody|MEP 50 antibody|MEP-50 antibody|MEP50 antibody|MEP50_HUMAN antibody|Methylosome protein 50 antibody|MGC2722 antibody|Nbla10071 antibody|p44 antibody|p44/Mep50 antibody|RGD1310479 antibody|RP11 552M11.3 antibody|WD repeat containing protein 77 antibody|WD repeat domain 77 antibody|WD repeat-containing protein 77 antibody|WDR77 antibody|Anti-WDR77 antibody [EPR10708(B)] (ab154190)
SCBT cat No:

Name

Anti-WDR77 antibody

Catalogue No.

STJ99206

Reactivity

Human, Mouse, Rat

Specificity

Anti-WDR77 antibody detects endogenous levels of WDR77 and does not cross-react with related proteins.

Immunogen

Purified recombinant human WDR77 protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Molecular weight

42kDa

Formulation

Anti-WDR77 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-WDR77 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

2610312E17Rik antibody, Androgen receptor cofactor p44 antibody, C79984 antibody, HKMT1069 antibody, MEP 50 antibody, MEP-50 antibody, MEP50 antibody, MEP50_HUMAN antibody, Methylosome protein 50 antibody, MGC2722 antibody, Nbla10071 antibody, p44 antibody, p44/Mep50 antibody, RGD1310479 antibody, RP11 552M11.3 antibody, WD repeat containing protein 77 antibody, WD repeat domain 77 antibody, WD repeat-containing protein 77 antibody, WDR77 antibody

Database links

UniProt/Swiss-Prot:Q9BQA1

Protein function

Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. .

Protein tissue specificity

Highly expressed in heart, skeletal muscle, spleen, testis, uterus, prostate and thymus. In testis, expressed in germ cells and Leydig cells, but not in peritubular myocytes, nor in Sertoli cells. Expressed in prostate cancers, in seminomas and in Leydig cell tumors. .

Protein sequence and domain

Contains 7 WD repeats.

Protein cellular localization

Nucleus. Cytoplasm. Note=Nuclear in Leydig cells and cytoplasmic in germ cells during fetal testicular development. In adult testis, predominantly nuclear. Subcellular location varies from nuclear to cytoplasmic in various tumors.

Note

AntibodyPlus can customize Anti-WDR77 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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