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Mouse Monoclonal ApoB antibody [6G6] (STJ97838)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IF, FC, ELISA
Recommended dilution: WB 1:500-1:2000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
Recommended protocols: check protocols
Click or hover above images to see image description for ApoB Monoclonal Antibody.
Check alternative names for the antibodyExpand
APOB antibody,|Apo B-100 antibody|Apo B-48 antibody|ApoB 100 antibody|ApoB 48 antibody|APOB antibody|APOB_HUMAN antibody|Apolipoprotein B 100 antibody|Apolipoprotein B antibody|Apolipoprotein B-48 antibody|Apolipoprotein B48 antibody|FLDB antibody|LDLCQ4 antibody|Anti-Apolipoprotein B antibody (ab20737)
SCBT cat No: sc-393636|sc-13538|sc-11797|sc-12332|sc-25542|sc-11795|sc-166508|sc-11735|
ApoB Monoclonal Antibody
|Catalogue No.|| |
ApoB Monoclonal Antibody detects endogenous levels of ApoB protein.
Purified recombinant fragment of human ApoB expressed in E Coli
WB, IF, FC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
ApoB Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
ApoB Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Apolipoprotein B-100 antibody, Apo B-100 antibody
|Protein names|| |
Apolipoprotein B-100 , Apo B-100
|Protein function|| |
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
|Protein tissue specificity|| |
Up-regulated in response to enterovirus 71 (EV71) infection (at protein level).
|Involvement in disease|| |
Hypobetalipoproteinemia, familial, 1 (FHBL1) [MIM:615558]: A disorder of lipid metabolism characterized by less than 5th percentile age- and sex-specific levels of low density lipoproteins, and dietary fat malabsorption. Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia. . Note: The disease is caused by mutations affecting the gene represented in this entry. Most cases of FHBL1 result from nonsense mutations in the APOB gene that lead to a premature stop codon, which generate prematurely truncated apo B protein products (PubMed:21981844). .; Familial ligand-defective apolipoprotein B-100 (FDB) [MIM:144010]: Dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease (CAD). The plasma cholesterol levels are dramatically elevated due to impaired clearance of LDL particles by defective APOB/E receptors. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Note: Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
|Protein sequence and domain|| |
Contains 1 vitellogenin domain.
|Protein post-translational modifications|| |
Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
|Protein cellular localization|| |
Cytoplasm / Secreted
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St John’s Laboratory Ltd.
|Product type|| |
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