Mouse Monoclonal ApoB antibody [6G6] (STJ97838)

$379.00

Reactivity: Human
Applications: WB, IF, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal ApoB antibody [6G6] (STJ97838)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IF, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for ApoB Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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APOB antibody,|Apo B-100 antibody|Apo B-48 antibody|ApoB 100 antibody|ApoB 48 antibody|APOB antibody|APOB_HUMAN antibody|Apolipoprotein B 100 antibody|Apolipoprotein B antibody|Apolipoprotein B-48 antibody|Apolipoprotein B48 antibody|FLDB antibody|LDLCQ4 antibody|Anti-Apolipoprotein B antibody (ab20737)
SCBT cat No: sc-393636|sc-13538|sc-11797|sc-12332|sc-25542|sc-11795|sc-166508|sc-11735|

 

Name

ApoB Monoclonal Antibody

Catalogue No.

STJ97838

Reactivity

Human

Specificity

ApoB Monoclonal Antibody detects endogenous levels of ApoB protein.

Immunogen

Purified recombinant fragment of human ApoB expressed in E Coli

Host

Mouse

Applications

WB, IF, FC, ELISA

Recommended dilution

WB 1:500-1:2000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

ApoB Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

ApoB Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Apolipoprotein B-100 antibody, Apo B-100 antibody

Database links

Human UniProt/Swiss-Prot:P04114;Mouse UniPort/Swiss-Prot: E9Q414;Rat UniProt/Swiss-Port: Q7TMA5;Human Entrez Gene: 338;Mouse Entrez Gene: 238055;Rat Entrez Gene: Rn.33815

Protein names

Apolipoprotein B-100 , Apo B-100

Protein function

Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.

Protein tissue specificity

Up-regulated in response to enterovirus 71 (EV71) infection (at protein level).

Involvement in disease

Hypobetalipoproteinemia, familial, 1 (FHBL1) [MIM:615558]: A disorder of lipid metabolism characterized by less than 5th percentile age- and sex-specific levels of low density lipoproteins, and dietary fat malabsorption. Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia. . Note: The disease is caused by mutations affecting the gene represented in this entry. Most cases of FHBL1 result from nonsense mutations in the APOB gene that lead to a premature stop codon, which generate prematurely truncated apo B protein products (PubMed:21981844). .; Familial ligand-defective apolipoprotein B-100 (FDB) [MIM:144010]: Dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease (CAD). The plasma cholesterol levels are dramatically elevated due to impaired clearance of LDL particles by defective APOB/E receptors. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Note: Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.

Protein sequence and domain

Contains 1 vitellogenin domain.

Protein post-translational modifications

Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.

Protein cellular localization

Cytoplasm / Secreted

Research area

All research areas>Transport and Trafficking>Apolipoprotein
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus can customize ApoB Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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