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Mouse Monoclonal Bax antibody [1C1] (STJ97729)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC
Recommended dilution: WB 1:1000-2000; IHC 1:100-200
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
BAX antibody, BCL2L4 antibody,|Apoptosis regulator BAX antibody|BAX antibody|Bax-protein antibody|BAX_HUMAN antibody|BAXA antibody|Baxdelta2G9 antibody|Baxdelta2G9omega antibody|Baxdelta2omega antibody|Bcl-2-like protein 4 antibody|BCL2 associated X protein antibody|BCL2 associated X protein omega antibody|BCL2 associated X protein transcript variant delta2 antibody|Bcl2-L-4 antibody|BCL2L4 antibody|membrane isoform alpha antibody|Anti-Bax antibody [E63] (ab32503)
SCBT cat No: sc-6236|sc-20067|sc-70407|sc-23959|sc-70405|sc-70408|sc-7480|sc-493|sc-526|sc-65532|sc-80658|sc-20288|
Bax Mouse Monoclonal Antibody(1C1)
|Catalogue No.|| |
Human, Mouse, Rat
Bax Mouse Monoclonal Antibody(1C1) detects endogenous levels of BAX
Synthetic Peptide of Bax at AA range of 30-110
|Recommended dilution|| |
WB 1:1000-2000; IHC 1:100-200
Bax Antibody(1C1) was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Bax Mouse Antibody(1C1) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Apoptosis regulator BAX antibody, Bcl-2-like protein 4 antibody, Bcl2-L-4 antibody
|Protein names|| |
Apoptosis regulator BAX , Bcl-2-like protein 4 , Bcl2-L-4
|Protein function|| |
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
|Protein tissue specificity|| |
Expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lung, colon, brain and at low levels in skin. Isoform Alpha and isoform Sigma are expressed in pro-myelocytic leukemia, histiocytic lymphoma, Burkitt’s lymphoma, T-cell lymphoma, lymphoblastic leukemia, breast adenocarcinoma, ovary adenocarcinoma, prostate carcinoma, prostate adenocarcinoma, lung carcinoma, epidermoid carcinoma, small cell lung carcinoma and colon adenocarcinoma cell lines.
|Protein sequence and domain|| |
Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family. / Belongs to the Bcl-2 family.
|Protein cellular localization|| |
Mitochondrion membrane; Single-pass membrane protein / Cytoplasm / Cytoplasm / Cytoplasm / Cytoplasm
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St John’s Laboratory Ltd.
|Product type|| |
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