Mouse Monoclonal Bcl-10 antibody [4F8] (STJ97859)

$379.00

Reactivity: Human, Mouse
Applications: WB, IHC, IF, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Bcl-10 antibody [4F8] (STJ97859)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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BCL10 antibody, CIPER antibody, CLAP antibody,|AI132454 antibody|B cell CLL/lymphoma 10 antibody|B cell lymphoma/leukemia10 antibody|B-cell CLL/lymphoma 10 antibody|B-cell leukemia/lymphoma 10 antibody|B-cell lymphoma/leukemia 10 antibody|Bcl 10 antibody|Bcl-10 antibody|Bcl10 antibody|BCL10_HUMAN antibody|c E10 antibody|c-E10 antibody|C81403 antibody|CARD containing apoptotic signaling protein antibody|CARD containing molecule enhancing NF kappa B antibody|CARD containing molecule enhancing NF kB antibody|CARD containing molecule enhancing NF-kB antibody|CARD containing molecule enhancing NFkB antibody|CARD containing proapoptotic protein antibody|CARD like apoptotic protein antibody|CARD-containing apoptotic signaling protein antibody|CARD-containing molecule enhancing NF-kappa-B antibody|CARD-containing proapoptotic protein antibody|CARD-like apoptotic protein antibody|CARMEN antibody|Caspase recruiting domain containing protein antibody|caspase-recruiting domain-containing protein antibody|cCARMEN antibody|cE 10 antibody|cE10 antibody|CED 3/ICH 1 prodomain homologous E10 like regulator antibody|CED-3/ICH-1 prodomain homologous E10-like regulator antibody|CED3/ICH1 prodomain homologous E10 like regulator antibody|Cellular E10 antibody|Cellular homolog of vCARMEN antibody|Cellular-E10 antibody|CIPER antibody|CLAP antibody|hCLAP antibody|Mammalian CARD containing adapter molecule E10 antibody|Mammalian CARD-containing adapter molecule E10 antibody|mE 10 antibody|mE10 antibody|R-RCD1 antibody|Anti-Bcl10 antibody [EP606Y] (ab33905)
SCBT cat No: sc-56023|sc-5273|sc-32808|sc-13153|sc-9560|sc-5611|sc-55511|sc-9558|sc-33093|

 

Name

Bcl-10 Monoclonal Antibody

Catalogue No.

STJ97859

Reactivity

Human, Mouse

Specificity

Bcl-10 Monoclonal Antibody detects endogenous levels of Bcl-10 protein.

Immunogen

Purified recombinant fragment of human Bcl-10 expressed in E Coli

Host

Mouse

Applications

WB, IHC, IF, FC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

Bcl-10 Antibody was tube-contained. Purified antibody in PBS containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Bcl-10 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

B-cell lymphoma/leukemia 10 antibody, B-cell CLL/lymphoma 10 antibody, Bcl-10 antibody, CARD-containing molecule enhancing NF-kappa-B antibody, CARD-like apoptotic protein antibody, hCLAP antibody, CED-3/ICH-1 prodomain homologous E10-like regulator antibody, CIPER antibody, Cellular homolog of vCARMEN antibody, cCARMEN antibody, Cellular-E10 antibody, c-E10 antibody, Mammalian CARD-containing adapter molecule E10 antibody, mE10 antibody

Database links

Human UniProt/Swiss-Prot:O95999;Mouse UniPort/Swiss-Prot: Q9Z0H7;Rat UniProt/Swiss-Port: Q9QYN5;Human Entrez Gene: 8915;Mouse Entrez Gene: 12042;Rat Entrez Gene: Rn.13007

Protein names

B-cell lymphoma/leukemia 10 , B-cell CLL/lymphoma 10 , Bcl-10 , CARD-containing molecule enhancing NF-kappa-B , CARD-like apoptotic protein , hCLAP , CED-3/ICH-1 prodomain homologous E10-like regulator , CIPER , Cellular homolog of vCARMEN , cCARMEN , Cellular-E10 , c-E10 , Mammalian CARD-containing adapter molecule E10 , mE10

Protein function

Involved in adaptive immune response . Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 .

Protein tissue specificity

Ubiquitous.

Involvement in disease

Note: A chromosomal aberration involving BCL10 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(1;14)(p22;q32). Although the BCL10/IgH translocation leaves the coding region of BCL10 intact, frequent BCL10 mutations could be attributed to the Ig somatic hypermutation mechanism resulting in nucleotide transitions.; Immunodeficiency 37 (IMD37) [MIM:616098]: A form of primary combined immunodeficiency, a group of disorders characterized by severe recurrent infections, with normal numbers or an absence of T and B lymphocytes, and impaired cellular and humoral immunity. IMD37 is characterized by hypogammaglobulinemia without lymphopenia, but with profoundly reduced memory B cells and memory T cells, and increased numbers of circulating naive lymphocytes. Inheritance is autosomal recessive. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 1 CARD domain.

Protein post-translational modifications

Phosphorylated. Phosphorylation results in dissociation from TRAF2 and binding to BIRC2/c-IAP2. Phosphorylated by IKBKB/IKKB.

Protein cellular localization

Cytoplasm > perinuclear region / Membrane raft

Research area

All research areas>Tumor Suppressor/Apoptosis>Bcl10
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize Bcl-10 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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