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Mouse Monoclonal BID antibody [3C5] (STJ97864)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, FC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
BID antibody,|Apoptic death agonist antibody|Apoptotic death agonist BID antibody|BH3 interacting domain death agonist antibody|BH3 interacting domain death agonist p11 antibody|BH3 interacting domain death agonist p13 antibody|BH3 interacting domain death agonist p15 antibody|BH3-interacting domain death agonist p11 antibody|BID antibody|BID isoform ES(1b) antibody|BID isoform L(2) antibody|BID isoform Si6 antibody|BID_HUMAN antibody|Desmocollin type 4 antibody|FP497 antibody|Human BID coding sequence antibody|MGC15319 antibody|MGC42355 antibody|p11 BID antibody|p13 BID antibody|p15 BID antibody|p22 BID antibody|Anti-Bid antibody [Y8] (ab32060)
SCBT cat No: sc-56025|sc-373939|sc-6538|sc-6291|sc-514622|sc-11423|sc-6539|sc-376866|
BID Monoclonal Antibody
|Catalogue No.|| |
BID Monoclonal Antibody detects endogenous levels of BID protein.
Purified recombinant fragment of human BID expressed in E Coli
WB, IHC, IF, FC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
BID Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
BID Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
BH3-interacting domain death agonist antibody, p22 BID antibody, BID antibody
|Protein names|| |
BH3-interacting domain death agonist , p22 BID , BID
|Protein function|| |
The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
|Protein tissue specificity|| |
Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).
|Protein sequence and domain|| |
Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
|Protein post-translational modifications|| |
TNF-alpha induces a caspase-mediated cleavage of p22 BID into a major p15 and minor p13 and p11 products. / p15 BID is ubiquitinated by ITCH; ubiquitination results in proteasome-dependent degradation.
|Protein cellular localization|| |
Cytoplasm / Mitochondrion membrane / Mitochondrion membrane / Mitochondrion membrane / Cytoplasm / Cytoplasm / Mitochondrion membrane
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St John’s Laboratory Ltd.
|Product type|| |
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