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Mouse Monoclonal BM28 antibody [2B3] (STJ97871)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, FC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
MCM2 antibody, BM28 antibody, CCNL1 antibody, CDCL1 antibody, KIAA0030 antibody,|BM28 antibody|CCNL 1 antibody|CCNL1 antibody|CDC like 1 antibody|cdc19 antibody|CDCL 1 antibody|CDCL1 antibody|Cell devision cycle like 1 antibody|Cyclin like 1 antibody|D3S3194 antibody|DNA replication licensing factor MCM2 antibody|KIAA0030 antibody|MCM 2 antibody|MCM2 antibody|MCM2 minichromosome maintenance deficient 2 mitotin antibody|MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) antibody|MCM2 minichromosome maintenance deficient 2, mitotin antibody|MCM2_HUMAN antibody|MGC10606 antibody|Minichromosome maintenance complex component 2 antibody|Minichromosome maintenance deficient 2 (mitotin) antibody|Minichromosome maintenance deficient 2 mitotin antibody|Minichromosome maintenance protein 2 antibody|Minichromosome maintenance protein 2 homolog antibody|Mitotin antibody|Nuclear protein BM28 antibody|OTTHUMP00000216047 antibody|OTTHUMP00000216050 antibody|Anti-MCM2 antibody (ab4461)
SCBT cat No: sc-56321|sc-73572|sc-373702|sc-10771|sc-9839|sc-56322|
BM28 Monoclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat, Monkey
BM28 Monoclonal Antibody detects endogenous levels of BM28 protein.
Purified recombinant fragment of human BM28 expressed in E Coli
WB, IHC, FC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
BM28 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
BM28 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
DNA replication licensing factor MCM2 antibody, Minichromosome maintenance protein 2 homolog antibody, Nuclear protein BM28 antibody
|Protein names|| |
DNA replication licensing factor MCM2 , Minichromosome maintenance protein 2 homolog , Nuclear protein BM28
|Protein function|| |
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ‘once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. / ATP + H2O = ADP + phosphate.
|Protein sequence and domain|| |
Belongs to the MCM family. / Contains 1 MCM domain.
|Protein post-translational modifications|| |
Phosphorylated on Ser-108 by ATR in proliferating cells. Ser-108 proliferation is increased by genotoxic agents. Ser-40 is mediated by the CDC7-DBF4 and CDC7-DBF4B complexes, while Ser-53 phosphorylation is only mediated by the CDC7-DBF4 complex. Phosphorylation by the CDC7-DBF4 complex during G1/S phase is required for the initiation of DNA replication.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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