Mouse Monoclonal BM28 antibody [2B3] (STJ97871)

$379.00

Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, IHC, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal BM28 antibody [2B3] (STJ97871)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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MCM2 antibody, BM28 antibody, CCNL1 antibody, CDCL1 antibody, KIAA0030 antibody,|BM28 antibody|CCNL 1 antibody|CCNL1 antibody|CDC like 1 antibody|cdc19 antibody|CDCL 1 antibody|CDCL1 antibody|Cell devision cycle like 1 antibody|Cyclin like 1 antibody|D3S3194 antibody|DNA replication licensing factor MCM2 antibody|KIAA0030 antibody|MCM 2 antibody|MCM2 antibody|MCM2 minichromosome maintenance deficient 2 mitotin antibody|MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) antibody|MCM2 minichromosome maintenance deficient 2, mitotin antibody|MCM2_HUMAN antibody|MGC10606 antibody|Minichromosome maintenance complex component 2 antibody|Minichromosome maintenance deficient 2 (mitotin) antibody|Minichromosome maintenance deficient 2 mitotin antibody|Minichromosome maintenance protein 2 antibody|Minichromosome maintenance protein 2 homolog antibody|Mitotin antibody|Nuclear protein BM28 antibody|OTTHUMP00000216047 antibody|OTTHUMP00000216050 antibody|Anti-MCM2 antibody (ab4461)
SCBT cat No: sc-56321|sc-73572|sc-373702|sc-10771|sc-9839|sc-56322|

 

Name

BM28 Monoclonal Antibody

Catalogue No.

STJ97871

Reactivity

Human, Mouse, Rat, Monkey

Specificity

BM28 Monoclonal Antibody detects endogenous levels of BM28 protein.

Immunogen

Purified recombinant fragment of human BM28 expressed in E Coli

Host

Mouse

Applications

WB, IHC, FC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

BM28 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

BM28 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

DNA replication licensing factor MCM2 antibody, Minichromosome maintenance protein 2 homolog antibody, Nuclear protein BM28 antibody

Database links

Human UniProt/Swiss-Prot:P49736;Mouse UniPort/Swiss-Prot: P97310;Rat UniProt/Swiss-Port: D3ZP96;Human Entrez Gene: 4171;Mouse Entrez Gene: 17216;Rat Entrez Gene: Rn.2715

Protein names

DNA replication licensing factor MCM2 , Minichromosome maintenance protein 2 homolog , Nuclear protein BM28

Protein function

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ‘once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. / ATP + H2O = ADP + phosphate.

Protein sequence and domain

Belongs to the MCM family. / Contains 1 MCM domain.

Protein post-translational modifications

Phosphorylated on Ser-108 by ATR in proliferating cells. Ser-108 proliferation is increased by genotoxic agents. Ser-40 is mediated by the CDC7-DBF4 and CDC7-DBF4B complexes, while Ser-53 phosphorylation is only mediated by the CDC7-DBF4 complex. Phosphorylation by the CDC7-DBF4 complex during G1/S phase is required for the initiation of DNA replication.

Protein cellular localization

Nucleus

Research area

All research areas>Cell Cycle Proteins>MCM
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize BM28 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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