Mouse Monoclonal BPTF antibody [2F10] (STJ97882)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal BPTF antibody [2F10] (STJ97882)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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BPTF antibody, FAC1 antibody, FALZ antibody,|Bromodomain and PHD finger containing transcription factor antibody|Bromodomain PHD finger transcription factor antibody|FAC 1 antibody|fac1 antibody|FALZ antibody|Fetal Alz 50 clone 1 protein antibody|Fetal Alz 50 reactive clone 1 antibody|Fetal Alzheimer antigen antibody|Nucleosome remodeling factor antibody|Nucleosome remodeling factor subunit BPTF antibody|Nucleosome remodeling factor, large subunit antibody|NURF 301 antibody|NURF301 antibody|Anti-BPTF / FALZ antibody (ab72036)
SCBT cat No: sc-81088|sc-98404|

 

Name

BPTF Monoclonal Antibody

Catalogue No.

STJ97882

Reactivity

Human

Specificity

BPTF Monoclonal Antibody detects endogenous levels of BPTF protein.

Immunogen

Purified recombinant fragment of human BPTF expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2b

Formulation

BPTF Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

BPTF Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Nucleosome-remodeling factor subunit BPTF antibody, Bromodomain and PHD finger-containing transcription factor antibody, Fetal Alz-50 clone 1 protein antibody, Fetal Alzheimer antigen antibody

Database links

Human UniProt/Swiss-Prot:Q12830;Human Entrez Gene: 2186;Mouse Entrez Gene: 207165;Rat Entrez Gene: Rn.49972

Protein names

Nucleosome-remodeling factor subunit BPTF , Bromodomain and PHD finger-containing transcription factor , Fetal Alz-50 clone 1 protein , Fetal Alzheimer antigen

Protein function

Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on ‘Lys-4’ (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.

Protein tissue specificity

Ubiquitously expressed, with highest levels in testis. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex (at protein level).

Protein sequence and domain

The second PHD-type zinc finger mediates binding to histone H3K4Me3. Has specificity for trimethyllysine; introducing a mutation in the Tyr-2876 residue can induce binding to dimethyllysine. / Belongs to the PBTF family. / Contains 1 bromo domain. / Contains 1 DDT domain. / Contains 2 PHD-type zinc fingers.

Protein post-translational modifications

Phosphorylation enhances DNA-binding. / Highly susceptible to proteolysis.

Protein cellular localization

Cytoplasm / Nucleus

Research area

All research areas>Cell Cycle Proteins>BPTF
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize BPTF Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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