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Mouse Monoclonal Calregulin antibody (KLH) [1G6A7] (STJ97892)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
CALR antibody, CRTC antibody,|Autoantigen RO antibody|CALR antibody|CALR protein antibody|CALR_HUMAN antibody|Calregulin antibody|Calreticulin antibody|cC1qR antibody|CRP55 antibody|CRT antibody|CRTC antibody|Endoplasmic reticulum resident protein 60 antibody|Epididymis secretory sperm binding protein Li 99n antibody|ERp60 antibody|FLJ26680 antibody|grp60 antibody|HACBP antibody|HEL S 99n antibody|RO antibody|Sicca syndrome antigen A (autoantigen Ro; calreticulin) antibody|Sicca syndrome antigen A antibody|SSA antibody|Anti-Calreticulin antibody (ab2907)
SCBT cat No: sc-101436|sc-166837|sc-6467|sc-373863|sc-166839|sc-11398|sc-6468|sc-7431|
Calregulin Monoclonal Antibody
|Catalogue No.|| |
Calregulin Monoclonal Antibody detects endogenous levels of Calregulin protein.
Synthetic peptide corresponding to aa (EEEDVPGQAKDELC) of human Calreticulin, conjugated to KLH
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000
Calregulin Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
Calregulin Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Calreticulin antibody, CRP55 antibody, Calregulin antibody, Endoplasmic reticulum resident protein 60 antibody, ERp60 antibody, HACBP antibody, grp60 antibody
|Protein names|| |
Calreticulin , CRP55 , Calregulin , Endoplasmic reticulum resident protein 60 , ERp60 , HACBP , grp60
|Protein function|| |
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).
|Protein sequence and domain|| |
Can be divided into a N-terminal globular domain, a proline-rich P-domain forming an elongated arm-like structure and a C-terminal acidic domain. The P-domain binds one molecule of calcium with high affinity, whereas the acidic C-domain binds multiple calcium ions with low affinity. / The interaction with glycans occurs through a binding site in the globular lectin domain. / The zinc binding sites are localized to the N-domain. / Associates with PDIA3 through the tip of the extended arm formed by the P-domain. / Belongs to the calreticulin family.
|Protein cellular localization|| |
Endoplasmic reticulum lumen / Cytoplasm > cytosol / Secreted > extracellular space > extracellular matrix / Cell surface / Sarcoplasmic reticulum lumen
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St John’s Laboratory Ltd.
|Product type|| |
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