Mouse Monoclonal Catenin-gamma antibody [4C12] (STJ97897)

$379.00

Reactivity: Human
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Catenin-gamma antibody [4C12] (STJ97897)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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JUP antibody, CTNNG antibody, DP3 antibody,|ARVD 12 antibody|ARVD12 antibody|Catenin (cadherin associated protein), gamma 80kDa antibody|catenin (cadherin-associated protein) gamma (80kD) antibody|Catenin gamma antibody|CTNNG antibody|Desmoplakin 3 antibody|Desmoplakin III antibody|Desmoplakin-3 antibody|Desmoplakin3 antibody|DesmoplakinIII antibody|DP 3 antibody|DP III antibody|DP3 antibody|DPIII antibody|gamma catenin antibody|Junction plakoglobin antibody|JUP antibody|OTTHUMP00000164732 antibody|OTTHUMP00000164735 antibody|OTTHUMP00000164738 antibody|PDGB antibody|PKGB antibody|PLAK_HUMAN antibody|PLAKOGLOBIN antibody|Anti-gamma Catenin antibody [EPR17310] (ab184919)
SCBT cat No: sc-59986|sc-33634|sc-514115|sc-514130|sc-1497|sc-398183|sc-514116|sc-30998|sc-8415|sc-7900|sc-30997|sc-30996|

 

Name

Catenin-gamma Monoclonal Antibody

Catalogue No.

STJ97897

Reactivity

Human

Specificity

Catenin-gamma Monoclonal Antibody detects endogenous levels of Catenin-gamma protein.

Immunogen

Purified recombinant fragment of human Catenin-gamma expressed in E Coli

Host

Mouse

Applications

WB, IHC, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

Catenin-gamma Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Catenin-gamma Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Junction plakoglobin antibody, Catenin gamma antibody, Desmoplakin III antibody, Desmoplakin-3 antibody

Database links

Human UniProt/Swiss-Prot:P14923;Mouse UniPort/Swiss-Prot: Q02257;Rat UniProt/Swiss-Port: Q6P0K8;Human Entrez Gene: 3728;Mouse Entrez Gene: 16480;Rat Entrez Gene: Rn.11255

Protein names

Junction plakoglobin , Catenin gamma , Desmoplakin III , Desmoplakin-3

Protein function

Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).

Involvement in disease

Naxos disease (NXD) [MIM:601214]: An autosomal recessive disorder characterized by the association of diffuse non-epidermolytic palmoplantar keratoderma with woolly hair and cardiac abnormalities such as dilated cardiomyopathy and arrhythmogenic right ventricular dysplasia. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Arrhythmogenic right ventricular dysplasia, familial, 12 (ARVD12) [MIM:611528]: A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

The entire ARM repeats region mediates binding to CDH1/E-cadherin. The N-terminus and first three ARM repeats are sufficient for binding to DSG1. The N-terminus and first ARM repeat are sufficient for association with CTNNA1. DSC1 association requires both ends of the ARM repeat region. / Belongs to the beta-catenin family. / Contains 12 ARM repeats.

Protein post-translational modifications

May be phosphorylated by FER.

Protein cellular localization

Cell junction > adherens junction / Cell junction > desmosome / Cytoplasm > cytoskeleton / Membrane / Peripheral membrane protein

Research area

All research areas>Cell Adhesion Proteins>Catenin
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize Catenin-gamma Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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