Mouse Monoclonal CCK-4 antibody [4F9] (STJ97900)

$379.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal CCK-4 antibody [4F9] (STJ97900)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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PTK7 antibody, CCK4 antibody,|8430404F20Rik antibody|CCK 4 antibody|CCK-4 antibody|Colon carcinoma kinase 4 antibody|Human colon carcinoma kinase 4 (CCK4) mRNA complete cds antibody|Inactive tyrosine-protein kinase 7 antibody|mPTK7/CCK4 antibody|OTTHUMP00000217016 antibody|Protein tyrosine kinase PTK 7 antibody|Protein-tyrosine kinase 7 antibody|Pseudo tyrosine kinase receptor 7 antibody|PTK 7 antibody|PTK7 antibody|PTK7 protein tyrosine kinase 7 antibody|PTK7 protein tyrosine kinase antibody|PTK7_HUMAN antibody|Serum response factor antibody|Srf antibody|Tyrosine-protein kinase-like 7 antibody|Anti-CCK4 antibody (ab117412)
SCBT cat No: sc-100304|

 

Name

CCK-4 Monoclonal Antibody

Catalogue No.

STJ97900

Reactivity

Human

Specificity

CCK-4 Monoclonal Antibody detects endogenous levels of CCK-4 protein.

Immunogen

Purified recombinant fragment of human CCK-4 expressed in E Coli

Host

Mouse

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

CCK-4 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

CCK-4 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Inactive tyrosine-protein kinase 7 antibody, Colon carcinoma kinase 4 antibody, CCK-4 antibody, Protein-tyrosine kinase 7 antibody, Pseudo tyrosine kinase receptor 7 antibody, Tyrosine-protein kinase-like 7 antibody

Database links

Human UniProt/Swiss-Prot:Q13308;Mouse UniPort/Swiss-Prot: Q8BKG3;Human Entrez Gene: 5754;Mouse Entrez Gene: 71461;Rat Entrez Gene: Rn.198822

Protein names

Inactive tyrosine-protein kinase 7 , Colon carcinoma kinase 4 , CCK-4 , Protein-tyrosine kinase 7 , Pseudo tyrosine kinase receptor 7 , Tyrosine-protein kinase-like 7

Protein function

Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

Protein tissue specificity

Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.

Protein sequence and domain

The protein kinase domain is predicted to be catalytically inactive. / Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. / Contains 7 Ig-like C2-type (immunoglobulin-like) domains. / Contains 1 protein kinase domain.

Protein post-translational modifications

MMP14 cleaves PTK7 between Pro-621 and Leu-622 generating an N-terminal soluble (70 kDa) fragment and a membrane C-terminal (50 kDa) fragment. Proteolysis by MMP14 regulates PTK7 function in non-canonical Wnt signaling pathway.

Protein cellular localization

Membrane / Single-pass type I membrane protein / Cell junction

Research area

All research areas>Membrane Receptors>Cholecystokinin Receptor
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize CCK-4 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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