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Mouse Monoclonal CD105 antibody [3A9] (STJ97903)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, FC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
ENG antibody, END antibody,|AI528660 antibody|AI662476 antibody|CD 105 antibody|CD105 antibody|CD105 antigen antibody|EGLN_HUMAN antibody|END antibody|Endoglin antibody|Eng antibody|FLJ41744 antibody|HHT1 antibody|ORW antibody|ORW1 antibody|Osler Rendu Weber syndrome 1 antibody|RP11 228B15.2 antibody|S-endoglin antibody|SN6 antibody|Anti-CD105 antibody [SN6] (ab11414)
SCBT cat No: sc-71042|sc-21787|sc-53999|sc-376381|sc-19790|sc-20632|sc-19793|sc-18893|sc-18838|sc-20072|sc-101443|
CD105 Monoclonal Antibody
|Catalogue No.|| |
CD105 Monoclonal Antibody detects endogenous levels of CD105 protein.
Purified recombinant fragment of human CD105 expressed in E Coli
WB, IHC, IF, FC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
CD105 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
CD105 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Endoglin antibody, CD antigen CD105 antibody
|Protein names|| |
Endoglin , CD antigen CD105
|Protein function|| |
Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
|Protein tissue specificity|| |
Endoglin is restricted to endothelial cells in all tissues except bone marrow.
|Involvement in disease|| |
Telangiectasia, hereditary hemorrhagic, 1 (HHT1) [MIM:187300]: A multisystemic vascular dysplasia leading to dilation of permanent blood vessels and arteriovenous malformations of skin, mucosa, and viscera. The disease is characterized by recurrent epistaxis and gastro-intestinal hemorrhage. Visceral involvement includes arteriovenous malformations of the lung, liver, and brain. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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