Mouse Monoclonal CD105 antibody [3A9] (STJ97903)

$379.00

Reactivity: Human
Applications: WB, IHC, IF, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal CD105 antibody [3A9] (STJ97903)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for CD105 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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ENG antibody, END antibody,|AI528660 antibody|AI662476 antibody|CD 105 antibody|CD105 antibody|CD105 antigen antibody|EGLN_HUMAN antibody|END antibody|Endoglin antibody|Eng antibody|FLJ41744 antibody|HHT1 antibody|ORW antibody|ORW1 antibody|Osler Rendu Weber syndrome 1 antibody|RP11 228B15.2 antibody|S-endoglin antibody|SN6 antibody|Anti-CD105 antibody [SN6] (ab11414)
SCBT cat No: sc-71042|sc-21787|sc-53999|sc-376381|sc-19790|sc-20632|sc-19793|sc-18893|sc-18838|sc-20072|sc-101443|

 

Name

CD105 Monoclonal Antibody

Catalogue No.

STJ97903

Reactivity

Human

Specificity

CD105 Monoclonal Antibody detects endogenous levels of CD105 protein.

Immunogen

Purified recombinant fragment of human CD105 expressed in E Coli

Host

Mouse

Applications

WB, IHC, IF, FC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

CD105 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

CD105 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Endoglin antibody, CD antigen CD105 antibody

Database links

Human UniProt/Swiss-Prot:P17813;Mouse UniPort/Swiss-Prot: Q63961;Rat UniProt/Swiss-Port: Q3KR75;Human Entrez Gene: 2022;Mouse Entrez Gene: 13805;Rat Entrez Gene: Rn.187025

Protein names

Endoglin , CD antigen CD105

Protein function

Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Protein tissue specificity

Endoglin is restricted to endothelial cells in all tissues except bone marrow.

Involvement in disease

Telangiectasia, hereditary hemorrhagic, 1 (HHT1) [MIM:187300]: A multisystemic vascular dysplasia leading to dilation of permanent blood vessels and arteriovenous malformations of skin, mucosa, and viscera. The disease is characterized by recurrent epistaxis and gastro-intestinal hemorrhage. Visceral involvement includes arteriovenous malformations of the lung, liver, and brain. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein cellular localization

Membrane; Single-pass type I membrane protein

Research area

All research areas>Membrane Receptors>Endoglin
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize CD105 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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