Mouse Monoclonal CD16 antibody (STJ96992)

$99.00$319.00

Reactivity: Human
Applications: WB, IHC
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal CD16 antibody (STJ96992)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB

Recommended dilution: WB 1:1000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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SCBT cat No: sc-70548|sc-19620|sc-52376|sc-65294|sc-20052|sc-19594|sc-20627|sc-51524|sc-51525|sc-19357|sc-58962|sc-68910|

Name

CD16 Monoclonal Antibody

Catalogue No.

STJ96992

Reactivity

Human

Specificity

The antibody detects endogenous CD16 protein.

Immunogen

Synthetic Peptide

Host

Mouse

Applications

WB

Recommended dilution

WB 1:1000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

CD16 Antibody was tube-contained. PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Purification

CD16 Antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Low affinity immunoglobulin gamma Fc region receptor III-A antibody, CD16a antigen antibody, Fc-gamma RIII-alpha antibody, Fc-gamma RIII antibody, Fc-gamma RIIIa antibody, FcRIII antibody, FcRIIIa antibody, FcR-10 antibody, IgG Fc receptor III-2 antibody, CD antigen CD16a antibody

Database links

Human UniProt/Swiss-Prot:P08637 ;Human Entrez Gene: 2214;

Protein names

Low affinity immunoglobulin gamma Fc region receptor III-A , CD16a antigen , Fc-gamma RIII-alpha , Fc-gamma RIII , Fc-gamma RIIIa , FcRIII , FcRIIIa , FcR-10 , IgG Fc receptor III-2 , CD antigen CD16a

Protein function

Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.

Protein tissue specificity

Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.

Involvement in disease

Immunodeficiency 20 (IMD20) [MIM:615707]: A rare autosomal recessive primary immunodeficiency characterized by functional deficiency of NK cells. Affected individuals typically present with severe herpes viral infections, particularly Epstein Barr virus (EBV), and human papillomavirus (HPV). . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Protein post-translational modifications

Glycosylated. Contains high mannose- and complex-type oligosaccharides. Glycosylation at Asn-180 is mandatory for high affinity binding to the Fc and for discrimination between fucosylated and afucosylated IgG glycoforms. / The soluble form is produced by a proteolytic cleavage.

Protein cellular localization

Cell membrane / Secreted

Research area

All research areas>Lymphocyte Signaling>CD16
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD16 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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Immunohistochemical analysis of paraffin embedded Human liver tissue

1: CD16 Monoclonal Antibody(Q32) was diluted at 1:200 (4 degree Celsius,overnight).
2: Sodium citrate pH 6.0 was used for antibody retrieval (>98 degree Celsius,20min).
3: Secondary antibody was diluted at 1:200 (room temperature, 30min). Negative control was used by secondary antibody only.
 

Immunohistochemical analysis of paraffin embedded Human kidney tissue

1: CD16 Monoclonal Antibody(Q32) was diluted at 1:200 (4 degree Celsius,overnight).
2: Sodium citrate pH 6.0 was used for antibody retrieval (>98 degree Celsius,20min).
3: Secondary antibody was diluted at 1:200 (room temperature, 30min). Negative control was used by secondary antibody only.


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