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Mouse Monoclonal CD18 antibody [10E12] (STJ97909)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IF, ELISA
Recommended dilution: IF 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
ITGB2 antibody, CD18 antibody, MFI7 antibody,|95 subunit beta antibody|Beta 2 (antigen CD18 (p95) antibody|CD 18 antibody|CD18 antibody|Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody|Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody|Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody|Complement component 3 receptor 3 and 4 subunit antibody|Complement receptor C3 beta subunit antibody|Complement receptor C3 subunit beta antibody|Integrin beta 2 antibody|Integrin beta chain beta 2 antibody|Integrin beta-2 (ITGB2) antibody|Integrin beta-2 antibody|Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody|ITB2_HUMAN antibody|ITGB2 antibody|LAD antibody|LCAMB antibody|Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody|Leukocyte cell adhesion molecule CD18 antibody|LFA 1 antibody|LFA1 antibody|Lymphocyte function associated antigen 1 (LFA1) antibody|Lymphocyte function associated antigen 1 antibody|MAC 1 antibody|MAC1 antibody|Macrophage antigen 1 (mac1) beta antibody|MF17 antibody|MFI7 antibody|OTTHUMP00000115278 antibody|OTTHUMP00000115279 antibody|OTTHUMP00000115280 antibody|OTTHUMP00000115281 antibody|OTTHUMP00000115282 antibody|Anti-CD18 antibody [MEM-48] (ab657)
SCBT cat No: sc-52684|sc-81632|sc-13588|sc-59970|sc-59971|sc-71453|sc-71454|sc-71455|sc-1185|sc-71456|sc-46676|sc-19989|sc-19618|sc-6619|sc-398708|sc-26692|
CD18 Monoclonal Antibody
|Catalogue No.|| |
CD18 Monoclonal Antibody detects endogenous levels of CD18 protein.
Purified recombinant fragment of CD18 expressed in E Coli
|Recommended dilution|| |
IF 1:200-1:1000; ELISA 1:10000
CD18 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
CD18 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Integrin beta-2 antibody, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta antibody, Complement receptor C3 subunit beta antibody, CD antigen CD18 antibody
|Protein names|| |
Integrin beta-2 , Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , Complement receptor C3 subunit beta , CD antigen CD18
|Protein function|| |
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.
|Involvement in disease|| |
Leukocyte adhesion deficiency 1 (LAD1) [MIM:116920]: LAD1 patients have recurrent bacterial infections and their leukocytes are deficient in a wide range of adhesion-dependent functions. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the integrin beta chain family. / Contains 1 VWFA domain.
|Protein post-translational modifications|| |
Both Ser-745 and Ser-756 become phosphorylated when T-cells are exposed to phorbol esters. Phosphorylation on Thr-758 (but not on Ser-756) allows interaction with 14-3-3 proteins.
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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