Mouse Monoclonal CD18 antibody [10E12] (STJ97909)

$379.00

Reactivity: Human, Mouse
Applications: IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal CD18 antibody [10E12] (STJ97909)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IF, ELISA

Recommended dilution: IF 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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ITGB2 antibody, CD18 antibody, MFI7 antibody,|95 subunit beta antibody|Beta 2 (antigen CD18 (p95) antibody|CD 18 antibody|CD18 antibody|Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody|Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody|Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody|Complement component 3 receptor 3 and 4 subunit antibody|Complement receptor C3 beta subunit antibody|Complement receptor C3 subunit beta antibody|Integrin beta 2 antibody|Integrin beta chain beta 2 antibody|Integrin beta-2 (ITGB2) antibody|Integrin beta-2 antibody|Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody|ITB2_HUMAN antibody|ITGB2 antibody|LAD antibody|LCAMB antibody|Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody|Leukocyte cell adhesion molecule CD18 antibody|LFA 1 antibody|LFA1 antibody|Lymphocyte function associated antigen 1 (LFA1) antibody|Lymphocyte function associated antigen 1 antibody|MAC 1 antibody|MAC1 antibody|Macrophage antigen 1 (mac1) beta antibody|MF17 antibody|MFI7 antibody|OTTHUMP00000115278 antibody|OTTHUMP00000115279 antibody|OTTHUMP00000115280 antibody|OTTHUMP00000115281 antibody|OTTHUMP00000115282 antibody|Anti-CD18 antibody [MEM-48] (ab657)
SCBT cat No: sc-52684|sc-81632|sc-13588|sc-59970|sc-59971|sc-71453|sc-71454|sc-71455|sc-1185|sc-71456|sc-46676|sc-19989|sc-19618|sc-6619|sc-398708|sc-26692|

 

Name

CD18 Monoclonal Antibody

Catalogue No.

STJ97909

Reactivity

Human, Mouse

Specificity

CD18 Monoclonal Antibody detects endogenous levels of CD18 protein.

Immunogen

Purified recombinant fragment of CD18 expressed in E Coli

Host

Mouse

Applications

IF, ELISA

Recommended dilution

IF 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

CD18 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

CD18 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Integrin beta-2 antibody, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta antibody, Complement receptor C3 subunit beta antibody, CD antigen CD18 antibody

Database links

Human UniProt/Swiss-Prot:P05107;Mouse UniPort/Swiss-Prot: P11835;Rat UniProt/Swiss-Port: B2RYB8;Human Entrez Gene: 3689;Mouse Entrez Gene: 16414;Rat Entrez Gene: Rn.42962

Protein names

Integrin beta-2 , Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , Complement receptor C3 subunit beta , CD antigen CD18

Protein function

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.

Involvement in disease

Leukocyte adhesion deficiency 1 (LAD1) [MIM:116920]: LAD1 patients have recurrent bacterial infections and their leukocytes are deficient in a wide range of adhesion-dependent functions. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the integrin beta chain family. / Contains 1 VWFA domain.

Protein post-translational modifications

Both Ser-745 and Ser-756 become phosphorylated when T-cells are exposed to phorbol esters. Phosphorylation on Thr-758 (but not on Ser-756) allows interaction with 14-3-3 proteins.

Protein cellular localization

Membrane; Single-pass type I membrane protein

Research area

All research areas>Cell Adhesion Proteins>Integrin
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize CD18 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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