Mouse Monoclonal CD3 antibody [4D10A6] (STJ97918)

$379.00

Reactivity: Human
Applications: FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal CD3 antibody [4D10A6] (STJ97918)

Supplier: St John’s Laboratory Ltd.

Recommended applications: FC, ELISA

Recommended dilution: FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

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SCBT cat No: sc-70617|sc-1239|sc-1124|sc-374281|sc-166435|sc-166275|sc-20919|sc-101411|sc-70628|sc-514271|sc-19658|

 

Name

CD3 Monoclonal Antibody

Catalogue No.

STJ97918

Reactivity

Human

Specificity

CD3 Monoclonal Antibody detects endogenous levels of CD3 protein.

Immunogen

Purified recombinant fragment of human CD3 expressed in E Coli

Host

Mouse

Applications

FC, ELISA

Recommended dilution

FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2a

Formulation

CD3 Antibody was tube-contained. Lyophilized from a 0.2mum filtered solution in PBS.

Concentration

1 mg/ml

Purification

CD3 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

T-cell surface glycoprotein CD3 zeta chain antibody, T-cell receptor T3 zeta chain antibody, CD antigen CD247 antibody

Database links

Human UniProt/Swiss-Prot:P20963;Mouse UniPort/Swiss-Prot: P24161;Rat UniProt/Swiss-Port: M0R576;Human Entrez Gene: 919;Mouse Entrez Gene: 12503;Rat Entrez Gene: Rn.9997

Protein names

T-cell surface glycoprotein CD3 zeta chain , T-cell receptor T3 zeta chain , CD antigen CD247

Protein function

Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.

Involvement in disease

Immunodeficiency 25 (IMD25) [MIM:610163]: An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

The ITAM domains mediate interaction with SHB. / Belongs to the CD3Z/FCER1G family. / Contains 3 ITAM domains.

Protein post-translational modifications

Phosphorylated on Tyr residues after T-cell receptor triggering.

Protein cellular localization

Membrane; Single-pass type I membrane protein

Research area

All research areas>Lymphocyte Signaling>CD3
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD3 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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