Mouse Monoclonal CD33 antibody [2B7C12] (STJ97921)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Mouse Monoclonal CD33 antibody [2B7C12] (STJ97921)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for CD33 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

CD33 antibody, SIGLEC3 antibody,|CD 33 antibody|CD33 antibody|CD33 antigen (gp67) antibody|CD33 antigen antibody|CD33 molecule antibody|CD33_HUMAN antibody|FLJ00391 antibody|gp67 antibody|My9 antibody|Myeloid cell surface antigen CD33 antibody|Myeloid cell surface antigen CD33 precursor antibody|Myeloid differentiation antigen CD33 antibody|p67 antibody|Sialic acid binding Ig like lectin 3 antibody|Sialic acid binding immunoglobulin like lectin 3 antibody|Sialic acid-binding Ig-like lectin 3 antibody|SIGLEC 3 antibody|Siglec-3 antibody|SIGLEC3 antibody|Anti-CD33 antibody [SP266] (ab199432)
SCBT cat No: sc-53199|sc-514119|sc-374450|sc-7038|sc-59020|sc-7041|sc-376184|sc-28811|sc-7040|

 

Name

CD33 Monoclonal Antibody

Catalogue No.

STJ97921

Reactivity

Human

Specificity

CD33 Monoclonal Antibody detects endogenous levels of CD33 protein.

Immunogen

Purified recombinant fragment of CD33 (48-258) expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

CD33 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

CD33 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Myeloid cell surface antigen CD33 antibody, Sialic acid-binding Ig-like lectin 3 antibody, Siglec-3 antibody, gp67 antibody, CD antigen CD33 antibody

Database links

Human UniProt/Swiss-Prot:P20138;Mouse UniPort/Swiss-Prot: Q63994;Human Entrez Gene: 945;Mouse Entrez Gene: 12489;

Protein names

Myeloid cell surface antigen CD33 , Sialic acid-binding Ig-like lectin 3 , Siglec-3 , gp67 , CD antigen CD33

Protein function

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Protein tissue specificity

Monocytic/myeloid lineage cells.

Protein sequence and domain

Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. / Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. / Contains 1 Ig-like C2-type (immunoglobulin-like) domain. / Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Protein post-translational modifications

Phosphorylation of Tyr-340 is involved in binding to PTPN6 and PTPN11. Phosphorylation of Tyr-358 is involved in binding to PTPN6.

Protein cellular localization

Cell membrane; Single-pass type I membrane protein

Research area

All research areas>Lymphocyte Signaling>CD33
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD33 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!