Mouse Monoclonal CD3E antibody [4E2] (STJ97925)

$379.00

Reactivity: Human
Applications: WB, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal CD3E antibody [4E2] (STJ97925)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, FC, ELISA

Recommended dilution: WB 1:500-1:2000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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CD3E antibody, T3E antibody,|CD3 epsilon antibody|CD3e antibody|CD3e antigen epsilon polypeptide (TiT3 complex) antibody|CD3E antigen epsilon polypeptide antibody|CD3E antigen, epsilon subunit antibody|CD3e molecule epsilon antibody|CD3e molecule, epsilon (CD3 TCR complex) antibody|CD3e molecule, epsilon (CD3-TCR complex) antibody|CD3E_HUMAN antibody|IMD18 antibody|T cell antigen receptor complex epsilon subunit of T3 antibody|T cell surface antigen T3/Leu 4 epsilon chain antibody|T cell surface glycoprotein CD3 epsilon chain antibody|T-cell surface antigen T3/Leu-4 epsilon chain antibody|T-cell surface glycoprotein CD3 epsilon chain antibody|T3E antibody|TCRE antibody|Anti-CD3 epsilon antibody [EP449E] (ab52959)
SCBT cat No: sc-20047|sc-1128|sc-137137|sc-30160|sc-1129|sc-26429|sc-26431|sc-18871|sc-1174|

 

Name

CD3E Monoclonal Antibody

Catalogue No.

STJ97925

Reactivity

Human

Specificity

CD3E Monoclonal Antibody detects endogenous levels of CD3E protein.

Immunogen

Purified recombinant fragment of CD3E expressed in E Coli

Host

Mouse

Applications

WB, FC, ELISA

Recommended dilution

WB 1:500-1:2000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

CD3E Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

CD3E Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

T-cell surface glycoprotein CD3 epsilon chain antibody, T-cell surface antigen T3/Leu-4 epsilon chain antibody, CD antigen CD3e antibody

Database links

Human UniProt/Swiss-Prot:P07766;Mouse UniPort/Swiss-Prot: P22646;Rat UniProt/Swiss-Port: D4A5M2;Human Entrez Gene: 916;Mouse Entrez Gene: 12501;Rat Entrez Gene: Rn.96221

Protein names

T-cell surface glycoprotein CD3 epsilon chain , T-cell surface antigen T3/Leu-4 epsilon chain , CD antigen CD3e

Protein function

The CD3 complex mediates signal transduction, resulting in T-cell activation and proliferation. Required for normal immune responses .

Involvement in disease

Immunodeficiency 18 (IMD18) [MIM:615615]: An autosomal recessive primary immunodeficiency characterized by onset in infancy or early childhood of recurrent infections. The severity is variable, encompassing both a mild immunodeficiency and severe combined immunodeficiency (SCID), resulting in early death without bone marrow transplantation in some patients. Immunologic work-up of the IMD18 SCID patients shows a T cell-negative, B cell-positive, natural killer (NK) cell-positive phenotype, whereas T-cell development is not impaired in the mild form of IMD18. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 1 Ig-like (immunoglobulin-like) domain. / Contains 1 ITAM domain.

Protein cellular localization

Cell membrane / Single-pass type I membrane protein

Research area

All research areas>Lymphocyte Signaling>CD3
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD3E Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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