Mouse Monoclonal CD71 antibody [2H9] (STJ97934)

$379.00

Reactivity: Human
Applications: WB, IHC, IF, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Mouse Monoclonal CD71 antibody [2H9] (STJ97934)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for CD71 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

TFRC antibody,|CD 71 antibody|CD71 antibody|CD71 antigen antibody|OTTHUMP00000208523 antibody|OTTHUMP00000208524 antibody|OTTHUMP00000208525 antibody|p90 antibody|sTfR antibody|T9 antibody|TFR 1 antibody|TfR antibody|TfR1 antibody|TFR1_HUMAN antibody|TFRC antibody|TR antibody|Transferrin receptor (p90 CD71) antibody|Transferrin receptor protein 1, serum form antibody|Trfr antibody|Anti-Transferrin Receptor antibody (ab84036)
SCBT cat No: sc-70778|sc-65877|sc-19675|

 

Name

CD71 Monoclonal Antibody

Catalogue No.

STJ97934

Reactivity

Human

Specificity

CD71 Monoclonal Antibody detects endogenous levels of CD71 protein.

Immunogen

Purified recombinant fragment of human CD71 expressed in E Coli

Host

Mouse

Applications

WB, IHC, IF, FC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

CD71 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

CD71 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Transferrin receptor protein 1 antibody, TR antibody, TfR antibody, TfR1 antibody, Trfr antibody, T9 antibody, p90 antibody, CD antigen CD71 antibody

Database links

Human UniProt/Swiss-Prot:P02786;Mouse UniPort/Swiss-Prot: Q62351;Rat UniProt/Swiss-Port: G3V679;Human Entrez Gene: 4155;Mouse Entrez Gene: 22042;Rat Entrez Gene: Rn.98672

Protein names

Transferrin receptor protein 1 , TR , TfR , TfR1 , Trfr , T9 , p90 , CD antigen CD71

Protein function

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. / (Microbial infection) Acts as a receptor for new-world arenaviruses: Guanarito, Junin and Machupo virus.

Protein tissue specificity

Regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3′-UTR. Up-regulated upon mitogenic stimulation.

Involvement in disease

Immunodeficiency 46 (IMD46) [MIM:616740]: An autosomal recessive primary immunodeficiency disorder characterized by early-onset chronic diarrhea, recurrent infections, hypo- or agammaglobulinemia, normal lymphocyte counts, intermittent neutropenia, and intermittent thrombocytopenia. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the peptidase M28 family. M28B subfamily. / Contains 1 PA (protease associated) domain.

Protein post-translational modifications

N- and O-glycosylated, phosphorylated and palmitoylated. The serum form is only glycosylated. / Proteolytically cleaved on Arg-100 to produce the soluble serum form (sTfR). / Palmitoylated on both Cys-62 and Cys-67. Cys-62 seems to be the major site of palmitoylation.

Protein cellular localization

Cell membrane / Single-pass type II membrane protein / Melanosome / Secreted

Research area

All research areas>Lymphocyte Signaling>CD71
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD71 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!