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Mouse Monoclonal CD8 antibody (STJ97936)
Supplier: St John’s Laboratory Ltd.
Recommended applications: FC, ELISA
Recommended dilution: FC 1:200-1:400; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
CD8A antibody, MAL antibody,|CD8 antibody|CD8 antigen, alpha polypeptide (p32) antibody|CD8a antibody|CD8a antigen antibody|CD8a molecule antibody|CD8A_HUMAN antibody|Leu2 antibody|Leu2 T lymphocyte antigen antibody|MAL antibody|OKT8 T cell antigen antibody|p32 antibody|T cell antigen Leu2 antibody|T cell co receptor antibody|T-cell surface glycoprotein CD8 alpha chain antibody|T-lymphocyte differentiation antigen T8/Leu-2 antibody|T8 T cell antigen antibody|Anti-CD8 antibody (ab4055)
SCBT cat No: sc-70794|sc-53675|sc-51735|sc-1181|sc-70791|sc-18913|sc-1141|
CD8 Monoclonal Antibody
|Catalogue No.|| |
CD8 Monoclonal Antibody detects endogenous levels of CD8 protein.
Purified recombinant fragment of human CD8 expressed in E Coli
|Recommended dilution|| |
FC 1:200-1:400; ELISA 1:10000
CD8 Antibody was tube-contained. Purified antibody in PBS containing 0.03% sodium azide.
CD8 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
T-cell surface glycoprotein CD8 alpha chain antibody, T-lymphocyte differentiation antigen T8/Leu-2 antibody, CD antigen CD8a antibody
|Protein names|| |
T-cell surface glycoprotein CD8 alpha chain , T-lymphocyte differentiation antigen T8/Leu-2 , CD antigen CD8a
|Protein function|| |
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
|Involvement in disease|| |
CD8 deficiency, familial (CD8 deficiency) [MIM:608957]: An immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
|Protein post-translational modifications|| |
All of the five most C-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.
|Protein cellular localization|| |
Cell membrane; Single-pass type I membrane protein / Secreted
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St John’s Laboratory Ltd.
|Product type|| |
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