Mouse Monoclonal CD8 antibody (STJ97936)

$379.00

Reactivity: Human
Applications: FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal CD8 antibody (STJ97936)

Supplier: St John’s Laboratory Ltd.

Recommended applications: FC, ELISA

Recommended dilution: FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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CD8A antibody, MAL antibody,|CD8 antibody|CD8 antigen, alpha polypeptide (p32) antibody|CD8a antibody|CD8a antigen antibody|CD8a molecule antibody|CD8A_HUMAN antibody|Leu2 antibody|Leu2 T lymphocyte antigen antibody|MAL antibody|OKT8 T cell antigen antibody|p32 antibody|T cell antigen Leu2 antibody|T cell co receptor antibody|T-cell surface glycoprotein CD8 alpha chain antibody|T-lymphocyte differentiation antigen T8/Leu-2 antibody|T8 T cell antigen antibody|Anti-CD8 antibody (ab4055)
SCBT cat No: sc-70794|sc-53675|sc-51735|sc-1181|sc-70791|sc-18913|sc-1141|

 

Name

CD8 Monoclonal Antibody

Catalogue No.

STJ97936

Reactivity

Human

Specificity

CD8 Monoclonal Antibody detects endogenous levels of CD8 protein.

Immunogen

Purified recombinant fragment of human CD8 expressed in E Coli

Host

Mouse

Applications

FC, ELISA

Recommended dilution

FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

CD8 Antibody was tube-contained. Purified antibody in PBS containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

CD8 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

T-cell surface glycoprotein CD8 alpha chain antibody, T-lymphocyte differentiation antigen T8/Leu-2 antibody, CD antigen CD8a antibody

Database links

Human UniProt/Swiss-Prot:P01732;Mouse UniPort/Swiss-Prot: P01731;Rat UniProt/Swiss-Port: P07725;Human Entrez Gene: 925;Mouse Entrez Gene: 12525;Rat Entrez Gene: Rn.10306

Protein names

T-cell surface glycoprotein CD8 alpha chain , T-lymphocyte differentiation antigen T8/Leu-2 , CD antigen CD8a

Protein function

Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.

Involvement in disease

CD8 deficiency, familial (CD8 deficiency) [MIM:608957]: An immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Protein post-translational modifications

All of the five most C-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.

Protein cellular localization

Cell membrane; Single-pass type I membrane protein / Secreted

Research area

All research areas>Lymphocyte Signaling>CD8
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD8 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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