Mouse Monoclonal CD86 antibody [1B3] (STJ97939)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal CD86 antibody [1B3] (STJ97939)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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CD86 antibody, CD28LG2 antibody,|Activation B7-2 antigen 3 antibody|Activation B7-2 antigen antibody|B-lymphocyte activation antigen B7-2 2 antibody|B-lymphocyte activation antigen B7-2 antibody|B7 2 antibody|B7 antibody|B7-2 antibody|B7.2 antibody|B70 antibody|B72 antigen antibody|BU63 antibody|CD28 antigen ligand 2 2 antibody|CD28 antigen ligand 2 antibody|Cd28l2 antibody|CD28LG2 antibody|CD86 antibody|CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 antibody|CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) antibody|CD86 antigen antibody|CD86 molecule antibody|CD86_HUMAN antibody|CLS1 antibody|CTLA-4 counter-receptor B7.2 2, 3 antibody|CTLA-4 counter-receptor B7.2 antibody|Early T-cell costimulatory molecule 1 antibody|ETC-1 antibody|FUN 1 antibody|FUN-1 antibody|LAB72 antibody|Ly-58 antibody|Ly58 antibody|MB7 antibody|MB7-2 antibody|Membrane glycoprotein antibody|MGC34413 antibody|T-lymphocyte activation antigen CD86 antibody|TS/A-2 antibody|Anti-CD86 antibody [EP1158Y] (ab53004)
SCBT cat No: sc-58915|sc-19617|sc-1635|sc-28347|sc-52448|sc-9092|

 

Name

CD86 Monoclonal Antibody

Catalogue No.

STJ97939

Reactivity

Human

Specificity

CD86 Monoclonal Antibody detects endogenous levels of CD86 protein.

Immunogen

Purified recombinant fragment of human CD86 expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

CD86 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

CD86 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

T-lymphocyte activation antigen CD86 antibody, Activation B7-2 antigen antibody, B70 antibody, BU63 antibody, CTLA-4 counter-receptor B7.2 antibody, FUN-1 antibody, CD antigen CD86 antibody

Database links

Human UniProt/Swiss-Prot:P42081;Mouse UniPort/Swiss-Prot: P42082;Rat UniProt/Swiss-Port: O35531;Human Entrez Gene: 942;Mouse Entrez Gene: 12524;Rat Entrez Gene: Rn.229570

Protein names

T-lymphocyte activation antigen CD86 , Activation B7-2 antigen , B70 , BU63 , CTLA-4 counter-receptor B7.2 , FUN-1 , CD antigen CD86

Protein function

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. / (Microbial infection) Acts as a receptor for adenovirus subgroup B.

Protein tissue specificity

Expressed by activated B-lymphocytes and monocytes.

Protein sequence and domain

Contains 1 Ig-like C2-type (immunoglobulin-like) domain. / Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Protein post-translational modifications

Polyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation.

Protein cellular localization

Cell membrane; Single-pass type I membrane protein

Research area

All research areas>Lymphocyte Signaling>B7-2
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CD86 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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