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Mouse Monoclonal Cystatin C antibody [5H2] (STJ97981)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
CST3 antibody,|AD 8 antibody|AD8 antibody|Amyloid angiopathy and cerebral hemorrhage antibody|ARMD11 antibody|bA218C14.4 (cystatin C) antibody|bA218C14.4 antibody|Cst 3 antibody|Cst3 antibody|CST3 protein antibody|Cystatin 3 antibody|Cystatin-3 antibody|Cystatin-C antibody|Cystatin3 antibody|CystatinC antibody|CYTC_HUMAN antibody|Gamma trace antibody|Gamma-trace antibody|HCCAA antibody|MGC117328 antibody|Neuroendocrine basic polypeptide antibody|Post gamma globulin antibody|Post-gamma-globulin antibody|Anti-Cystatin C antibody [EPR4413] (ab109508)
SCBT cat No: sc-293159|sc-73878|sc-51857|sc-66100|sc-16989|sc-73879|
Cystatin C Monoclonal Antibody
|Catalogue No.|| |
Cystatin C Monoclonal Antibody detects endogenous levels of Cystatin C protein.
Purified recombinant fragment of human Cystatin C expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
Cystatin C Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
Cystatin C Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Cystatin-C antibody, Cystatin-3 antibody, Gamma-trace antibody, Neuroendocrine basic polypeptide antibody, Post-gamma-globulin antibody
|Protein names|| |
Cystatin-C , Cystatin-3 , Gamma-trace , Neuroendocrine basic polypeptide , Post-gamma-globulin
|Protein function|| |
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
|Protein tissue specificity|| |
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
|Involvement in disease|| |
Amyloidosis 6 (AMYL6) [MIM:105150]: A hereditary generalized amyloidosis due to cystatin C amyloid deposition. Cystatin C amyloid accumulates in the walls of arteries, arterioles, and sometimes capillaries and veins of the brain, and in various organs including lymphoid tissue, spleen, salivary glands, and seminal vesicles. Amyloid deposition in the cerebral vessels results in cerebral amyloid angiopathy, cerebral hemorrhage and premature stroke. Cystatin C levels in the cerebrospinal fluid are abnormally low. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Macular degeneration, age-related, 11 (ARMD11) [MIM:611953]: A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the cystatin family.
|Protein post-translational modifications|| |
The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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