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Mouse Monoclonal Dkk-3 antibody [4G7] (STJ98001)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, FC, ELISA
Recommended dilution: WB 1:500-1:2000; FC 1:200-1:400; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
DKK3 antibody, REIC antibody, UNQ258/PRO295 antibody,|Dickkopf 3 antibody|Dickkopf3 antibody|DKK 3 antibody|Dkk-3 antibody|DKK3 antibody|DKK3_HUMAN antibody|hDkk 3 antibody|hDkk-3 antibody|hDkk3 antibody|Regulated in glioma antibody|REIC antibody|RIG antibody|RIG-like 5-6 antibody|RIG-like 7-1 antibody|Anti-Dkk3 antibody [EPR15611] (ab186409)
SCBT cat No: sc-517200|sc-14959|sc-25518|sc-14956|
Dkk-3 Monoclonal Antibody
|Catalogue No.|| |
Dkk-3 Monoclonal Antibody detects endogenous levels of Dkk-3 protein.
Purified recombinant fragment of human Dkk-3 expressed in E Coli
WB, FC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; FC 1:200-1:400; ELISA 1:10000
Dkk-3 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
Dkk-3 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Dickkopf-related protein 3 antibody, Dickkopf-3 antibody, Dkk-3 antibody, hDkk-3 antibody
|Protein names|| |
Dickkopf-related protein 3 , Dickkopf-3 , Dkk-3 , hDkk-3
|Protein function|| |
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
|Protein tissue specificity|| |
Highest expression in heart, brain, and spinal cord.
|Protein sequence and domain|| |
The C-terminal cysteine-rich domain mediates interaction with LRP5 and LRP6. / Belongs to the dickkopf family.
|Protein post-translational modifications|| |
N- and O-glycosylated.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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