Mouse Monoclonal Dkk-3 antibody [4G7] (STJ98001)

$379.00

Reactivity: Human, Monkey
Applications: WB, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Dkk-3 antibody [4G7] (STJ98001)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, FC, ELISA

Recommended dilution: WB 1:500-1:2000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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DKK3 antibody, REIC antibody, UNQ258/PRO295 antibody,|Dickkopf 3 antibody|Dickkopf3 antibody|DKK 3 antibody|Dkk-3 antibody|DKK3 antibody|DKK3_HUMAN antibody|hDkk 3 antibody|hDkk-3 antibody|hDkk3 antibody|Regulated in glioma antibody|REIC antibody|RIG antibody|RIG-like 5-6 antibody|RIG-like 7-1 antibody|Anti-Dkk3 antibody [EPR15611] (ab186409)
SCBT cat No: sc-517200|sc-14959|sc-25518|sc-14956|

 

Name

Dkk-3 Monoclonal Antibody

Catalogue No.

STJ98001

Reactivity

Human, Monkey

Specificity

Dkk-3 Monoclonal Antibody detects endogenous levels of Dkk-3 protein.

Immunogen

Purified recombinant fragment of human Dkk-3 expressed in E Coli

Host

Mouse

Applications

WB, FC, ELISA

Recommended dilution

WB 1:500-1:2000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

Dkk-3 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Dkk-3 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Dickkopf-related protein 3 antibody, Dickkopf-3 antibody, Dkk-3 antibody, hDkk-3 antibody

Database links

Human UniProt/Swiss-Prot:Q9UBP4;Mouse UniPort/Swiss-Prot: Q9QUN9;Rat UniProt/Swiss-Port: B1H219;Human Entrez Gene: 27122;Mouse Entrez Gene: 50781;Rat Entrez Gene: Rn.12516

Protein names

Dickkopf-related protein 3 , Dickkopf-3 , Dkk-3 , hDkk-3

Protein function

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Protein tissue specificity

Highest expression in heart, brain, and spinal cord.

Protein sequence and domain

The C-terminal cysteine-rich domain mediates interaction with LRP5 and LRP6. / Belongs to the dickkopf family.

Protein post-translational modifications

N- and O-glycosylated.

Protein cellular localization

Secreted

Research area

All research areas>Signaling Intermediates>Dkk-3
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Dkk-3 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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