Mouse Monoclonal Eg5 antibody (STJ98489)

$379.00

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig
Applications: WB, IF
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Mouse Monoclonal Eg5 antibody (STJ98489)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IF

Recommended dilution: WB 1:1000-1:2000; IF 1:100-1:500

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Eg5 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

KIF11 antibody, EG5 antibody, KNSL1 antibody, TRIP5 antibody,|EG5 antibody|KNSL1 antibody|MCLMR antibody|Thyroid receptor-interacting protein 5 antibody|TR-interacting protein 5 antibody|TRIP-5 antibody|TRIP5 antibody|Anti-Eg5 antibody [mAbcam 51976] (ab51976)
SCBT cat No: sc-53691|sc-136223|sc-365681|sc-365593|sc-393311|

 

Name

Eg5 Monoclonal Antibody

Catalogue No.

STJ98489

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig

Specificity

Eg5 Monoclonal Antibody detects endogenous levels of Eg5 protein.

Immunogen

Purified recombinant human Eg5 protein fragments expressed in Ecoli

Host

Mouse

Applications

WB, IF

Recommended dilution

WB 1:1000-1:2000; IF 1:100-1:500

Clonality

Monoclonal

Conjugation

Unconjugated

Formulation

Eg5 Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Concentration

1 mg/ml

Purification

Eg5 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Kinesin-like protein KIF11 antibody, Kinesin-like protein 1 antibody, Kinesin-like spindle protein HKSP antibody, Kinesin-related motor protein Eg5 antibody, Thyroid receptor-interacting protein 5 antibody, TR-interacting protein 5 antibody, TRIP-5 antibody

Database links

Human UniProt/Swiss-Prot:P52732;Mouse UniPort/Swiss-Prot: Q6P9P6;Rat UniProt/Swiss-Port: F1MAB8;Human Entrez Gene: 3832;Mouse Entrez Gene: 16551;Rat Entrez Gene: Rn.58850

Protein names

Kinesin-like protein KIF11 , Kinesin-like protein 1 , Kinesin-like spindle protein HKSP , Kinesin-related motor protein Eg5 , Thyroid receptor-interacting protein 5 , TR-interacting protein 5 , TRIP-5

Protein function

Motor protein required for establishing a bipolar spindle during mitosis . Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface .

Involvement in disease

Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation (MCLMR) [MIM:152950]: An autosomal dominant disorder that involves an overlapping but variable spectrum of central nervous system and ocular developmental anomalies. Microcephaly ranges from mild to severe and is often associated with mild to moderate developmental delay and a characteristic facial phenotype with upslanting palpebral fissures, broad nose with rounded tip, long philtrum with thin upper lip, prominent chin, and prominent ears. Chorioretinopathy is the most common eye abnormality, but retinal folds, microphthalmia, and myopic and hypermetropic astigmatism have also been reported, and some individuals have no overt ocular phenotype. Congenital lymphedema, when present, is typically confined to the dorsa of the feet, and lymphoscintigraphy reveals the absence of radioactive isotope uptake from the webspaces between the toes. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily. / Contains 1 kinesin motor domain.

Protein post-translational modifications

Phosphorylated exclusively on serine during S phase, but on both serine and Thr-926 during mitosis, so controlling the association of KIF11 with the spindle apparatus (probably during early prophase). / A subset of this protein primarily localized at the spindle pole is phosphorylated by NEK6 during mitosis; phosphorylation is required for mitotic function.

Protein cellular localization

Cytoplasm / Cytoplasm > cytoskeleton > spindle pole

Research area

All research areas>Structural Proteins>Eg5
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus can customize Eg5 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!