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Mouse Monoclonal EGF antibody [4E11] (STJ98013)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
EGF antibody,|Beta urogastrone antibody|EGF antibody|EGF_HUMAN antibody|Epidermal growth factor antibody|HOMG4 antibody|OTTHUMP00000219721 antibody|OTTHUMP00000219722 antibody|Pro epidermal growth factor antibody|URG antibody|Urogastrone antibody|Anti-EGF antibody (ab9695)
SCBT cat No: sc-1342|
EGF Monoclonal Antibody
|Catalogue No.|| |
EGF Monoclonal Antibody detects endogenous levels of EGF protein.
Purified recombinant fragment of human EGF expressed in E Coli
WB, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000
EGF Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
EGF Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Pro-epidermal growth factor antibody, EGF antibody
|Protein names|| |
Pro-epidermal growth factor , EGF
|Protein function|| |
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro .
|Protein tissue specificity|| |
Expressed in kidney, salivary gland, cerebrum and prostate.
|Involvement in disease|| |
Hypomagnesemia 4 (HOMG4) [MIM:611718]: A disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to moderate psychomotor retardation, and brisk tendon reflexes. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Contains 9 EGF-like domains. / Contains 9 LDL-receptor class B repeats.
|Protein post-translational modifications|| |
O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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