Mouse Monoclonal EphA1 antibody [5D2] (STJ98022)

$379.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal EphA1 antibody [5D2] (STJ98022)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for EphA1 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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EPHA1 antibody, EPH antibody, EPHT antibody, EPHT1 antibody,|EPH antibody|EPH receptor A1 antibody|EPH tyrosine kinase 1 antibody|EPH tyrosine kinase antibody|Epha1 antibody|EPHA1_HUMAN antibody|Ephrin receptor Eph A1 antibody|Ephrin type A receptor 1 antibody|Ephrin type-A receptor 1 antibody|EPHT 1 antibody|EPHT antibody|EPHT1 antibody|Erythropoietin producing hepatoma amplified sequence antibody|Erythropoietin-producing hepatoma receptor antibody|Esk antibody|hEpha1 antibody|MGC163163 antibody|Oncogene EPH antibody|Soluble EPHA1 variant 1 antibody|Soluble EPHA1 variant 2 antibody|Tyrosine protein kinase receptor EPH antibody|Tyrosine-protein kinase receptor EPH antibody|Anti-Eph receptor A1 antibody (ab5376)
SCBT cat No: sc-65994|sc-65993|sc-31257|sc-925|sc-20738|

 

Name

EphA1 Monoclonal Antibody

Catalogue No.

STJ98022

Reactivity

Human

Specificity

EphA1 Monoclonal Antibody detects endogenous levels of EphA1 protein.

Immunogen

Purified recombinant fragment of EphA1 expressed in E Coli

Host

Mouse

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

EphA1 Antibody was tube-contained. Purified antibody in PBS containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

EphA1 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Ephrin type-A receptor 1 antibody, hEpha1 antibody, EPH tyrosine kinase antibody, EPH tyrosine kinase 1 antibody, Erythropoietin-producing hepatoma receptor antibody, Tyrosine-protein kinase receptor EPH antibody

Database links

Human UniProt/Swiss-Prot:P21709;Mouse UniPort/Swiss-Prot: Q60750;Rat UniProt/Swiss-Port: D3ZDH4;Human Entrez Gene: 2041;Mouse Entrez Gene: 13835;Rat Entrez Gene: Rn.218221

Protein names

Ephrin type-A receptor 1 , hEpha1 , EPH tyrosine kinase , EPH tyrosine kinase 1 , Erythropoietin-producing hepatoma receptor , Tyrosine-protein kinase receptor EPH

Protein function

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis. / ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Protein tissue specificity

Overexpressed in several carcinomas.

Protein sequence and domain

Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. / Contains 1 Eph LBD (Eph ligand-binding) domain. / Contains 2 fibronectin type-III domains. / Contains 1 protein kinase domain. / Contains 1 SAM (sterile alpha motif) domain.

Protein post-translational modifications

Phosphorylated. Autophosphorylation is stimulated by its ligand EFNA1. / Ubiquitinated.

Protein cellular localization

Cell membrane / Single-pass type I membrane protein

Research area

All research areas>Membrane Receptors>Eph
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize EphA1 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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