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Mouse Monoclonal EphA1 antibody [5D2] (STJ98022)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
EPHA1 antibody, EPH antibody, EPHT antibody, EPHT1 antibody,|EPH antibody|EPH receptor A1 antibody|EPH tyrosine kinase 1 antibody|EPH tyrosine kinase antibody|Epha1 antibody|EPHA1_HUMAN antibody|Ephrin receptor Eph A1 antibody|Ephrin type A receptor 1 antibody|Ephrin type-A receptor 1 antibody|EPHT 1 antibody|EPHT antibody|EPHT1 antibody|Erythropoietin producing hepatoma amplified sequence antibody|Erythropoietin-producing hepatoma receptor antibody|Esk antibody|hEpha1 antibody|MGC163163 antibody|Oncogene EPH antibody|Soluble EPHA1 variant 1 antibody|Soluble EPHA1 variant 2 antibody|Tyrosine protein kinase receptor EPH antibody|Tyrosine-protein kinase receptor EPH antibody|Anti-Eph receptor A1 antibody (ab5376)
SCBT cat No: sc-65994|sc-65993|sc-31257|sc-925|sc-20738|
EphA1 Monoclonal Antibody
|Catalogue No.|| |
EphA1 Monoclonal Antibody detects endogenous levels of EphA1 protein.
Purified recombinant fragment of EphA1 expressed in E Coli
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
EphA1 Antibody was tube-contained. Purified antibody in PBS containing 0.03% sodium azide.
EphA1 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Ephrin type-A receptor 1 antibody, hEpha1 antibody, EPH tyrosine kinase antibody, EPH tyrosine kinase 1 antibody, Erythropoietin-producing hepatoma receptor antibody, Tyrosine-protein kinase receptor EPH antibody
|Protein names|| |
Ephrin type-A receptor 1 , hEpha1 , EPH tyrosine kinase , EPH tyrosine kinase 1 , Erythropoietin-producing hepatoma receptor , Tyrosine-protein kinase receptor EPH
|Protein function|| |
Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis. / ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
|Protein tissue specificity|| |
Overexpressed in several carcinomas.
|Protein sequence and domain|| |
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. / Contains 1 Eph LBD (Eph ligand-binding) domain. / Contains 2 fibronectin type-III domains. / Contains 1 protein kinase domain. / Contains 1 SAM (sterile alpha motif) domain.
|Protein post-translational modifications|| |
Phosphorylated. Autophosphorylation is stimulated by its ligand EFNA1. / Ubiquitinated.
|Protein cellular localization|| |
Cell membrane / Single-pass type I membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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