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Mouse Monoclonal EphA7 antibody [6C8G7] (STJ98029)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
EPHA7 antibody, EHK3 antibody, HEK11 antibody,|Cek 11 antibody|Developmental kinase 1 antibody|EBK antibody|EHK-3 antibody|EHK3 antibody|EK11 antibody|Embryonic brain kinase antibody|EPH homology kinase 3 antibody|EPH-like kinase 11 antibody|Epha7 antibody|EPHA7_HUMAN antibody|Ephrin receptor Eph A7 antibody|Ephrin type A receptor 7 antibody|Ephrin type-A receptor 7 antibody|hEK11 antibody|MDK 1 antibody|Receptor protein tyrosine kinase HEK 11 antibody|Tyrosine protein kinase receptor EHK 3 antibody|Anti-Eph receptor A7 antibody (ab204113)
SCBT cat No: sc-1015|sc-393974|sc-365647|sc-917|
EphA7 Monoclonal Antibody
|Catalogue No.|| |
EphA7 Monoclonal Antibody detects endogenous levels of EphA7 protein.
Purified recombinant fragment of EphA7 (aa27-210) expressed in E Coli
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
EphA7 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
EphA7 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Ephrin type-A receptor 7 antibody, EPH homology kinase 3 antibody, EHK-3 antibody, EPH-like kinase 11 antibody, EK11 antibody, hEK11 antibody
|Protein names|| |
Ephrin type-A receptor 7 , EPH homology kinase 3 , EHK-3 , EPH-like kinase 11 , EK11 , hEK11
|Protein function|| |
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7. / ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. / Contains 1 Eph LBD (Eph ligand-binding) domain. / Contains 2 fibronectin type-III domains. / Contains 1 protein kinase domain. / Contains 1 SAM (sterile alpha motif) domain.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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