Mouse Monoclonal EphA7 antibody [6C8G7] (STJ98029)

$379.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal EphA7 antibody [6C8G7] (STJ98029)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for EphA7 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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EPHA7 antibody, EHK3 antibody, HEK11 antibody,|Cek 11 antibody|Developmental kinase 1 antibody|EBK antibody|EHK-3 antibody|EHK3 antibody|EK11 antibody|Embryonic brain kinase antibody|EPH homology kinase 3 antibody|EPH-like kinase 11 antibody|Epha7 antibody|EPHA7_HUMAN antibody|Ephrin receptor Eph A7 antibody|Ephrin type A receptor 7 antibody|Ephrin type-A receptor 7 antibody|hEK11 antibody|MDK 1 antibody|Receptor protein tyrosine kinase HEK 11 antibody|Tyrosine protein kinase receptor EHK 3 antibody|Anti-Eph receptor A7 antibody (ab204113)
SCBT cat No: sc-1015|sc-393974|sc-365647|sc-917|

 

Name

EphA7 Monoclonal Antibody

Catalogue No.

STJ98029

Reactivity

Human

Specificity

EphA7 Monoclonal Antibody detects endogenous levels of EphA7 protein.

Immunogen

Purified recombinant fragment of EphA7 (aa27-210) expressed in E Coli

Host

Mouse

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2b

Formulation

EphA7 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

EphA7 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Ephrin type-A receptor 7 antibody, EPH homology kinase 3 antibody, EHK-3 antibody, EPH-like kinase 11 antibody, EK11 antibody, hEK11 antibody

Database links

Human UniProt/Swiss-Prot:Q15375;Mouse UniPort/Swiss-Prot: Q61772;Rat UniProt/Swiss-Port: P54759;Human Entrez Gene: 2045;Mouse Entrez Gene: 13841;Rat Entrez Gene: Rn.10181

Protein names

Ephrin type-A receptor 7 , EPH homology kinase 3 , EHK-3 , EPH-like kinase 11 , EK11 , hEK11

Protein function

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7. / ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Protein tissue specificity

Widely expressed.

Protein sequence and domain

Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. / Contains 1 Eph LBD (Eph ligand-binding) domain. / Contains 2 fibronectin type-III domains. / Contains 1 protein kinase domain. / Contains 1 SAM (sterile alpha motif) domain.

Protein post-translational modifications

Phosphorylated.

Protein cellular localization

Cell membrane

Research area

All research areas>Membrane Receptors>Eph
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize EphA7 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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