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Mouse Monoclonal ER81 antibody [1C8B6] (STJ98041)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
ETV1 antibody, ER81 antibody,|DKFZp781L0674 antibody|Etsrp81 antibody|ETV 1 antibody|ETV1 antibody|ETV1_HUMAN antibody|MGC104699 antibody|MGC120533 antibody|MGC120534 antibody|Anti-ER81 antibody (ab184120)
SCBT cat No: sc-293155|sc-1953|sc-28681|sc-1954|
ER81 Monoclonal Antibody
|Catalogue No.|| |
ER81 Monoclonal Antibody detects endogenous levels of ER81 protein.
Purified recombinant fragment of ER81 (aa1-191) expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
ER81 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
ER81 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
ETS translocation variant 1 antibody, Ets-related protein 81 antibody
|Protein names|| |
ETS translocation variant 1 , Ets-related protein 81
|Protein function|| |
Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5′-CGGA[AT]-3′.
|Protein tissue specificity|| |
Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
|Involvement in disease|| |
Ewing sarcoma (ES) [MIM:612219]: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. . Note: The gene represented in this entry is involved in disease pathogenesis. A chromosomal aberration involving ETV1 is found in patients with Erwing sarcoma. Translocation t(7;22)(p22;q12) with EWSR1. .
|Protein sequence and domain|| |
Belongs to the ETS family. / Contains 1 ETS DNA-binding domain.
|Protein post-translational modifications|| |
Sumoylated. / Phosphorylated at Ser-191 and Ser-216 by RPS6KA1 and RPS6KA5; phosphorylation activates transcriptional activity.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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