Mouse Monoclonal ER81 antibody [1C8B6] (STJ98041)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal ER81 antibody [1C8B6] (STJ98041)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ETV1 antibody, ER81 antibody,|DKFZp781L0674 antibody|Etsrp81 antibody|ETV 1 antibody|ETV1 antibody|ETV1_HUMAN antibody|MGC104699 antibody|MGC120533 antibody|MGC120534 antibody|Anti-ER81 antibody (ab184120)
SCBT cat No: sc-293155|sc-1953|sc-28681|sc-1954|

 

Name

ER81 Monoclonal Antibody

Catalogue No.

STJ98041

Reactivity

Human

Specificity

ER81 Monoclonal Antibody detects endogenous levels of ER81 protein.

Immunogen

Purified recombinant fragment of ER81 (aa1-191) expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

ER81 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

ER81 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

ETS translocation variant 1 antibody, Ets-related protein 81 antibody

Database links

Human UniProt/Swiss-Prot:P50549;Mouse UniPort/Swiss-Prot: P41164;Rat UniProt/Swiss-Port: B5DEZ2;Human Entrez Gene: 2115;Mouse Entrez Gene: 14009;Rat Entrez Gene: Rn.56219

Protein names

ETS translocation variant 1 , Ets-related protein 81

Protein function

Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5′-CGGA[AT]-3′.

Protein tissue specificity

Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.

Involvement in disease

Ewing sarcoma (ES) [MIM:612219]: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. . Note: The gene represented in this entry is involved in disease pathogenesis. A chromosomal aberration involving ETV1 is found in patients with Erwing sarcoma. Translocation t(7;22)(p22;q12) with EWSR1. .

Protein sequence and domain

Belongs to the ETS family. / Contains 1 ETS DNA-binding domain.

Protein post-translational modifications

Sumoylated. / Phosphorylated at Ser-191 and Ser-216 by RPS6KA1 and RPS6KA5; phosphorylation activates transcriptional activity.

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>ER81
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize ER81 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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