Mouse Monoclonal ERK 3 antibody [4E8] (STJ98048)

$379.00

Reactivity: Human
Applications: WB, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal ERK 3 antibody [4E8] (STJ98048)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, FC, ELISA

Recommended dilution: WB 1:500-1:2000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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MAPK6 antibody, ERK3 antibody, PRKM6 antibody,|ERK-3 antibody|ERK3 antibody|Extracellular signal regulated kinase 3 antibody|Extracellular signal regulated kinase p97 antibody|Extracellular signal-regulated kinase 3 antibody|HsT17250 antibody|MAP kinase 6 antibody|MAP kinase isoform p97 antibody|MAPK 6 antibody|MAPK6 antibody|Mitogen activated protein kinase 6 antibody|Mitogen-activated protein kinase 6 antibody|MK06_HUMAN antibody|p97 MAPK antibody|p97-MAPK antibody|PRKM6 antibody|Protein kinase mitogen activated 5 antibody|Protein kinase mitogen activated 6 antibody|Anti-MAPK6 antibody [EP1720Y] (ab53277)
SCBT cat No: sc-365234|sc-155|sc-374239|sc-393371|sc-156|

 

Name

ERK 3 Monoclonal Antibody

Catalogue No.

STJ98048

Reactivity

Human

Specificity

ERK 3 Monoclonal Antibody detects endogenous levels of ERK 3 protein.

Immunogen

Purified recombinant fragment of human ERK 3 expressed in E Coli

Host

Mouse

Applications

WB, FC, ELISA

Recommended dilution

WB 1:500-1:2000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

ERK 3 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

ERK 3 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Mitogen-activated protein kinase 6 antibody, MAP kinase 6 antibody, MAPK 6 antibody, Extracellular signal-regulated kinase 3 antibody, ERK-3 antibody, MAP kinase isoform p97 antibody, p97-MAPK antibody

Database links

Human UniProt/Swiss-Prot:Q16659;Mouse UniPort/Swiss-Prot: Q61532;Rat UniProt/Swiss-Port: P27704;Human Entrez Gene: 5597;Mouse Entrez Gene: 50772;Rat Entrez Gene: Rn.88457

Protein names

Mitogen-activated protein kinase 6 , MAP kinase 6 , MAPK 6 , Extracellular signal-regulated kinase 3 , ERK-3 , MAP kinase isoform p97 , p97-MAPK

Protein function

Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity). / ATP + a protein = ADP + a phosphoprotein. / Mg2+ / Activated by phosphorylation at Ser-189.

Protein tissue specificity

Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Protein sequence and domain

In contrast to classical MAPKs, the TXY motif within the activation loop is replaced by the SEG motif, whose phosphorylation activates the MAP kinases. / Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. / Contains 1 protein kinase domain.

Protein post-translational modifications

Phosphorylated at Ser-189 by PAK1, PAK2 and PAK3 resulting in catalytic activation. Phosphorylated by MAPKAPK5 at other sites. / Ubiquitination at Met-1 leads to degradation by the proteasome pathway.

Protein cellular localization

Cytoplasm / Nucleus

Research area

All research areas>Kinases and Phosphatases>ERK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize ERK 3 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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