No products in the cart.
Mouse Monoclonal FAS antibody (STJ98491)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB
Recommended dilution: WB 1:1000-1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for FAS Monoclonal Antibody.
Check alternative names for the antibodyExpand
FAS antibody, APT1 antibody, FAS1 antibody, TNFRSF6 antibody,|ALPS 1A antibody|ALPS1A antibody|APO 1 antibody|Apo 1 antigen antibody|APO 1 cell surface antigen antibody|Apo-1 antigen antibody|APO1 antibody|Apo1 antigen antibody|APO1 cell surface antigen antibody|Apoptosis antigen 1 antibody|Apoptosis mediating surface antigen FAS antibody|Apoptosis-mediating surface antigen FAS antibody|APT 1 antibody|APT1 antibody|CD 95 antibody|CD 95 antigen antibody|CD95 antibody|CD95 antigen antibody|Delta Fas antibody|Delta Fas/APO 1/CD95 antibody|Delta Fas/APO1/CD95 antibody|Fas (TNF receptor superfamily, member 6) antibody|FAS 1 antibody|FAS 827dupA antibody|Fas AMA antibody|Fas antibody|FAS Antigen antibody|Fas cell surface death receptor antibody|FAS1 antibody|FASLG receptor antibody|FASTM antibody|sFAS antibody|Surface antigen APO1 antibody|TNF receptor superfamily, member 6 antibody|TNFRSF 6 antibody|TNFRSF6 antibody|TNR6_HUMAN antibody|Tumor necrosis factor receptor superfamily member 6 antibody|Anti-Fas antibody (ab82419)
SCBT cat No: sc-8009|sc-715|sc-21730|sc-7886|sc-74540|sc-716|sc-714|
FAS Monoclonal Antibody
|Catalogue No.|| |
FAS Monoclonal Antibody detects endogenous levels of FAS protein.
Purified recombinant human FAS (C-terminus) protein fragments expressed in Ecoli
|Recommended dilution|| |
FAS Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
FAS Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Tumor necrosis factor receptor superfamily member 6 antibody, Apo-1 antigen antibody, Apoptosis-mediating surface antigen FAS antibody, FASLG receptor antibody, CD antigen CD95 antibody
|Protein names|| |
Tumor necrosis factor receptor superfamily member 6 , Apo-1 antigen , Apoptosis-mediating surface antigen FAS , FASLG receptor , CD antigen CD95
|Protein function|| |
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
|Protein tissue specificity|| |
Isoform 1 and isoform 6 are expressed at equal levels in resting peripheral blood mononuclear cells. After activation there is an increase in isoform 1 and decrease in the levels of isoform 6.
|Involvement in disease|| |
Autoimmune lymphoproliferative syndrome 1A (ALPS1A) [MIM:601859]: A disorder of apoptosis that manifests in early childhood and results in the accumulation of autoreactive lymphocytes. It is characterized by non-malignant lymphadenopathy with hepatosplenomegaly, and autoimmune hemolytic anemia, thrombocytopenia and neutropenia. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Contains a death domain involved in the binding of FADD, and maybe to other cytosolic adapter proteins. / Contains 1 death domain. / Contains 3 TNFR-Cys repeats.
|Protein post-translational modifications|| |
N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.
|Protein cellular localization|| |
Cell membrane; Single-pass type I membrane protein / Secreted / Secreted / Secreted / Secreted / Secreted
AntibodyPlus can customize FAS Antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: