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Mouse Monoclonal FoxP2 antibody [5C11A2] (STJ98087)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
FOXP2 antibody, CAGH44 antibody, TNRC10 antibody,|CAG repeat protein 44 antibody|CAGH44 antibody|DKFZp686H1726 antibody|Forkhead box P2 antibody|Forkhead box protein P2 antibody|forkhead/winged-helix transcription factor antibody|FOX P2 antibody|FOXP2 antibody|FOXP2_HUMAN antibody|HGNC11222 antibody|HGNC11956 antibody|SPCH 1 antibody|SPCH1 antibody|TNRC 10 antibody|TNRC10 antibody|trinucleotide repeat containing 10 antibody|Trinucleotide repeat containing gene 10 protein antibody|Trinucleotide repeat-containing gene 10 protein antibody|Anti-FOXP2 antibody (ab16046)
SCBT cat No: sc-517193|sc-31737|sc-66897|sc-21069|
FoxP2 Monoclonal Antibody
|Catalogue No.|| |
FoxP2 Monoclonal Antibody detects endogenous levels of FoxP2 protein.
Purified recombinant fragment of human FoxP2 expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
FoxP2 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
FoxP2 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Forkhead box protein P2 antibody, CAG repeat protein 44 antibody, Trinucleotide repeat-containing gene 10 protein antibody
|Protein names|| |
Forkhead box protein P2 , CAG repeat protein 44 , Trinucleotide repeat-containing gene 10 protein
|Protein function|| |
Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
|Protein tissue specificity|| |
Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung.
|Involvement in disease|| |
Speech-language disorder 1 (SPCH1) [MIM:602081]: A disorder characterized by severe orofacial dyspraxia resulting in largely incomprehensible speech. Affected individuals have severe impairment in the selection and sequencing of fine orofacial movements which are necessary for articulation, and deficits in several facets of grammatical skills and language processing, such as the ability to break up words into their constituent phonemes. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Note: A chromosomal aberration involving FOXP2 is a cause of severe speech and language impairment. Translocation t(5;7)(q22;q31.2).
|Protein sequence and domain|| |
The leucine-zipper is required for dimerization and transcriptional repression. / Contains 1 C2H2-type zinc finger. / Contains 1 fork-head DNA-binding domain.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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