Mouse Monoclonal FoxP2 antibody [5C11A8] (STJ98086)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal FoxP2 antibody [5C11A8] (STJ98086)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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FOXP2 antibody, CAGH44 antibody, TNRC10 antibody,|CAG repeat protein 44 antibody|CAGH44 antibody|DKFZp686H1726 antibody|Forkhead box P2 antibody|Forkhead box protein P2 antibody|forkhead/winged-helix transcription factor antibody|FOX P2 antibody|FOXP2 antibody|FOXP2_HUMAN antibody|HGNC11222 antibody|HGNC11956 antibody|SPCH 1 antibody|SPCH1 antibody|TNRC 10 antibody|TNRC10 antibody|trinucleotide repeat containing 10 antibody|Trinucleotide repeat containing gene 10 protein antibody|Trinucleotide repeat-containing gene 10 protein antibody|Anti-FOXP2 antibody (ab16046)
SCBT cat No: sc-517193|sc-31737|sc-66897|sc-21069|

 

Name

FoxP2 Monoclonal Antibody

Catalogue No.

STJ98086

Reactivity

Human

Specificity

FoxP2 Monoclonal Antibody detects endogenous levels of FoxP2 protein.

Immunogen

Purified recombinant fragment of human FoxP2 expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

FoxP2 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

FoxP2 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Forkhead box protein P2 antibody, CAG repeat protein 44 antibody, Trinucleotide repeat-containing gene 10 protein antibody

Database links

Human UniProt/Swiss-Prot:O15409;Mouse UniPort/Swiss-Prot: P58463;Rat UniProt/Swiss-Port: P0CF24;Human Entrez Gene: 93986;Mouse Entrez Gene: 114142;Rat Entrez Gene: Rn.134464

Protein names

Forkhead box protein P2 , CAG repeat protein 44 , Trinucleotide repeat-containing gene 10 protein

Protein function

Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.

Protein tissue specificity

Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung.

Involvement in disease

Speech-language disorder 1 (SPCH1) [MIM:602081]: A disorder characterized by severe orofacial dyspraxia resulting in largely incomprehensible speech. Affected individuals have severe impairment in the selection and sequencing of fine orofacial movements which are necessary for articulation, and deficits in several facets of grammatical skills and language processing, such as the ability to break up words into their constituent phonemes. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Note: A chromosomal aberration involving FOXP2 is a cause of severe speech and language impairment. Translocation t(5;7)(q22;q31.2).

Protein sequence and domain

The leucine-zipper is required for dimerization and transcriptional repression. / Contains 1 C2H2-type zinc finger. / Contains 1 fork-head DNA-binding domain.

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>FOXP2
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize FoxP2 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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