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Mouse Monoclonal Fyb antibody (STJ98493)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB
Recommended dilution: WB 1:1000-1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Fyb Monoclonal Antibody.
Check alternative names for the antibodyExpand
FYB antibody, SLAP130 antibody,|ADAP antibody|Adhesion and degranulation promoting adaptor protein antibody|FYB 120/130 antibody|Fyb antibody|FYB-120/130 antibody|FYB_HUMAN antibody|FYN binding protein antibody|FYN T binding protein antibody|FYN-binding protein antibody|FYN-T-binding protein antibody|p120/p130 antibody|PRO0823 antibody|SLAP 130 antibody|SLAP-130 antibody|SLAP130 antibody|SLP 76 associated phosphoprotein antibody|SLP-76-associated phosphoprotein antibody|SLP76 associated phosphoprotein antibody|Anti-FYB antibody [EP2546Y] (ab76103)
SCBT cat No: sc-135913|sc-7105|sc-515372|sc-393276|
Fyb Monoclonal Antibody
|Catalogue No.|| |
Fyb Monoclonal Antibody detects endogenous levels of Fyb protein.
Purified recombinant human Fyb protein fragments expressed in Ecoli
|Recommended dilution|| |
Fyb Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Fyb Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
FYN-binding protein antibody, Adhesion and degranulation promoting adaptor protein antibody, ADAP antibody, FYB-120/130 antibody, p120/p130 antibody, FYN-T-binding protein antibody, SLAP-130 antibody, SLP-76-associated phosphoprotein antibody
|Protein names|| |
FYN-binding protein , Adhesion and degranulation promoting adaptor protein , ADAP , FYB-120/130 , p120/p130 , FYN-T-binding protein , SLAP-130 , SLP-76-associated phosphoprotein
|Protein function|| |
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.
|Protein tissue specificity|| |
Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
|Protein sequence and domain|| |
Contains 1 SH3 domain.
|Protein post-translational modifications|| |
T-cell receptor ligation leads to increased tyrosine phosphorylation.
|Protein cellular localization|| |
Cytoplasm / Nucleus / Cell junction
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St John’s Laboratory Ltd.
|Product type|| |
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