Mouse Monoclonal G6PD antibody [5E12] (STJ98093)

$379.00

Reactivity: Human
Applications: WB, IHC, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal G6PD antibody [5E12] (STJ98093)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for G6PD Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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G6PD antibody,|G6PD antibody|G6PD_HUMAN antibody|G6PD1 antibody|G6pdx antibody|Glucose 6 phosphate 1 dehydrogenase antibody|Glucose 6 phosphate dehydrogenase antibody|Glucose 6 phosphate dehydrogenase, G6PD antibody|Glucose-6-phosphate 1-dehydrogenase antibody|MET19 antibody|POS10 antibody|Zwf1p antibody|Anti-Glucose 6 Phosphate Dehydrogenase antibody (ab993)
SCBT cat No: sc-46968|sc-373886|sc-373887|sc-67165|sc-46971|

 

Name

G6PD Monoclonal Antibody

Catalogue No.

STJ98093

Reactivity

Human

Specificity

G6PD Monoclonal Antibody detects endogenous levels of G6PD protein.

Immunogen

Purified recombinant fragment of human G6PD expressed in E Coli

Host

Mouse

Applications

WB, IHC, FC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

G6PD Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

G6PD Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Glucose-6-phosphate 1-dehydrogenase antibody, G6PD antibody,

Database links

Human UniProt/Swiss-Prot:P11413;Mouse UniPort/Swiss-Prot: Q00612;Rat UniProt/Swiss-Port: P05370;Human Entrez Gene: 2539;Mouse Entrez Gene: 14381;Rat Entrez Gene: Rn.11040

Protein names

Glucose-6-phosphate 1-dehydrogenase , G6PD ,

Protein function

Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. / D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH. / 7.07 µM for NADP / 52 µM for glucose 6-phosphate /

Protein tissue specificity

Isoform Long is found in lymphoblasts, granulocytes and sperm.

Involvement in disease

Anemia, non-spherocytic hemolytic, due to G6PD deficiency (NSHA) [MIM:300908]: A disease characterized by G6PD deficiency, acute hemolytic anemia, fatigue, back pain, and jaundice. In most patients, the disease is triggered by an exogenous agent, such as some drugs, food, or infection. Increased unconjugated bilirubin, lactate dehydrogenase, and reticulocytosis are markers of the disorder. Although G6PD deficiency can be life-threatening, most patients are asymptomatic throughout their life. . Note: The disease is caused by mutations affecting the gene represented in this entry. Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of NSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity.

Protein sequence and domain

Belongs to the glucose-6-phosphate dehydrogenase family.

Protein post-translational modifications

Acetylated by ELP3 at Lys-403; acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403; deacetylation stimulates its enzyme activity.

Research area

All research areas>Synthesis and Degradation>G6PD
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize G6PD Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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