Mouse Monoclonal GATA-3 antibody [1A10D1] (STJ98099)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal GATA-3 antibody [1A10D1] (STJ98099)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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GATA3 antibody,|GATA 3 antibody|GATA binding factor 3 antibody|GATA binding protein 3 antibody|GATA-binding factor 3 antibody|Gata3 antibody|GATA3_HUMAN antibody|HDR antibody|HDRS antibody|MGC2346 antibody|MGC5199 antibody|MGC5445 antibody|Trans acting T cell specific transcription factor GATA 3 antibody|Trans-acting T-cell-specific transcription factor GATA-3 antibody|Anti-GATA3 antibody [EPR16651] – ChIP Grade (ab199428)
SCBT cat No: sc-130057|sc-22205|sc-137152|sc-514427|sc-1236|sc-22206|sc-9009|sc-268|sc-269|

 

Name

GATA-3 Monoclonal Antibody

Catalogue No.

STJ98099

Reactivity

Human

Specificity

GATA-3 Monoclonal Antibody detects endogenous levels of GATA-3 protein.

Immunogen

Purified recombinant fragment of GATA-3 (aa175-388) expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

GATA-3 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

GATA-3 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Trans-acting T-cell-specific transcription factor GATA-3 antibody, GATA-binding factor 3 antibody

Database links

Human UniProt/Swiss-Prot:P23771;Mouse UniPort/Swiss-Prot: P23772;Rat UniProt/Swiss-Port: Q99NH5;Human Entrez Gene: 2624;Mouse Entrez Gene: 14462;Rat Entrez Gene: Rn.229174

Protein names

Trans-acting T-cell-specific transcription factor GATA-3 , GATA-binding factor 3

Protein function

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5′-AGATAG-3′. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.

Protein tissue specificity

T-cells and endothelial cells.

Involvement in disease

Hypoparathyroidism, sensorineural deafness, and renal disease (HDR) [MIM:146255]: A disease characterized by steroid-resistant nephrosis with progressive renal failure, hypoparathyroidism, sensorineural deafness, and renal dysplasia. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Binds DNA via the 2 GATA-type zinc fingers. Each zinc finger may bind either adjacent sites in a palindromic motif, or a different DNA molecule allowing looping and long-range gene regulation. / The YxKxHxxxRP motif is critical for DNA-binding and function. / Contains 2 GATA-type zinc fingers.

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>GATA
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize GATA-3 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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