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Mouse Monoclonal GATA-3 antibody [1A10D1] (STJ98099)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
GATA3 antibody,|GATA 3 antibody|GATA binding factor 3 antibody|GATA binding protein 3 antibody|GATA-binding factor 3 antibody|Gata3 antibody|GATA3_HUMAN antibody|HDR antibody|HDRS antibody|MGC2346 antibody|MGC5199 antibody|MGC5445 antibody|Trans acting T cell specific transcription factor GATA 3 antibody|Trans-acting T-cell-specific transcription factor GATA-3 antibody|Anti-GATA3 antibody [EPR16651] – ChIP Grade (ab199428)
SCBT cat No: sc-130057|sc-22205|sc-137152|sc-514427|sc-1236|sc-22206|sc-9009|sc-268|sc-269|
GATA-3 Monoclonal Antibody
|Catalogue No.|| |
GATA-3 Monoclonal Antibody detects endogenous levels of GATA-3 protein.
Purified recombinant fragment of GATA-3 (aa175-388) expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
GATA-3 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
GATA-3 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Trans-acting T-cell-specific transcription factor GATA-3 antibody, GATA-binding factor 3 antibody
|Protein names|| |
Trans-acting T-cell-specific transcription factor GATA-3 , GATA-binding factor 3
|Protein function|| |
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5′-AGATAG-3′. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.
|Protein tissue specificity|| |
T-cells and endothelial cells.
|Involvement in disease|| |
Hypoparathyroidism, sensorineural deafness, and renal disease (HDR) [MIM:146255]: A disease characterized by steroid-resistant nephrosis with progressive renal failure, hypoparathyroidism, sensorineural deafness, and renal dysplasia. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Binds DNA via the 2 GATA-type zinc fingers. Each zinc finger may bind either adjacent sites in a palindromic motif, or a different DNA molecule allowing looping and long-range gene regulation. / The YxKxHxxxRP motif is critical for DNA-binding and function. / Contains 2 GATA-type zinc fingers.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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